Potential role of exosomes in the chemoresistance to gemcitabine and nab-paclitaxel in pancreatic cancer

A Comandatore, B Immordino, R Balsano, M Capula… - Diagnostics, 2022 - mdpi.com
In recent years, a growing number of studies have evaluated the role of exosomes in
pancreatic ductal adenocarcinoma cancer (PDAC) demonstrating their involvement in a …

Unravelling the Role of Cancer Cell-Derived Extracellular Vesicles in Muscle Atrophy, Lipolysis, and Cancer-Associated Cachexia

AL Marzan, SV Chitti - Cells, 2023 - mdpi.com
Cancer-associated cachexia is a metabolic syndrome that causes significant reduction in
whole-body weight due to excessive loss of muscle mass accompanied by loss of fat mass …

The emerging role of extracellular vesicle derived from neurons/neurogliocytes in central nervous system diseases: novel insights into ischemic stroke

F Li, X Kang, W Xin, X Li - Frontiers in Pharmacology, 2022 - frontiersin.org
Neurons and neurogliocytes (oligodendrocytes, astrocytes, and microglia) are essential for
maintaining homeostasis of the microenvironment in the central nervous system (CNS) …

A Current Synopsis of the Emerging Role of Extracellular Vesicles and Micro-RNAs in Pancreatic Cancer: A Forward-Looking Plan for Diagnosis and Treatment

EM Trifylli, AG Kriebardis, E Koustas… - International Journal of …, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies worldwide,
while it persists as the fourth most prevalent cause of cancer-related death in the United …

Extracellular Vesicle‐Loaded Oncogenic lncRNA NEAT1 from Adipose‐Derived Mesenchymal Stem Cells Confers Gemcitabine Resistance in Pancreatic Cancer via …

R Wu, Z Su, L Zhao, R Pei, Y Ding, D Li… - Stem Cells …, 2023 - Wiley Online Library
It is becoming increasingly evident that key mechanisms of mesenchymal stem cell (MSC)
efficacy appear to associate with paracrine activities, and the delivery of cargos through …

Calix [6] arene dismantles extracellular vesicle biogenesis and metalloproteinases that support pancreatic cancer hallmarks

HG Cordeiro, JM Azevedo-Martins, AV de Sousa Faria… - Cellular …, 2024 - Elsevier
Many challenges are faced in pancreatic cancer treatment due to late diagnosis and poor
prognosis because of high recurrence and metastasis. Extracellular vesicles (EVs) and …

[HTML][HTML] Emerging Horizons in the Diagnosis of Pancreatic Cancer: The Role of Circulating microRNAs as Early Detection Biomarkers for Pancreatic Ductal …

I Reyaz, B Khan, N James, H Azhar, A Rehman… - Cureus, 2024 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a poor
prognosis, primarily due to a late diagnosis. Recent studies have focused on identifying non …

Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by …

T Zhang, H Yu, Y Bai, J Song, J Chen… - Immunopharmacology …, 2023 - Taylor & Francis
Objective The involvement of tumor-derived extracellular vesicles (EVs) in macrophage
polarization has been reported. In our present study, we tried to discuss the regulatory role …