There have been several clinical studies using chimeric antigen receptor (CAR)-T cell
therapy for different hematological malignancies. It has transformed the therapy landscape …

Oncolytic viruses (OVs) represent a potential therapeutic strategy in cancer treatment.
However, there is currently a lack of comprehensive quantitative models characterizing …

In this study, a mathematical model of triple negative breast cancer (TNBC) with checkpoint
inhibitor immunotherapy is proposed. The mathematical model includes interactions …

Cancer is recognized as one of the serious diseases threatening human health. Oncolytic
therapy is a safe and effective new cancer treatment method. Considering the limited ability …

We propose and study a mathematical model governing interactions between cancer and
immune system with an oncolytic viral therapy (OVT), wherein cancer cells can activate and …

CAR-T cell therapies have demonstrated significant success in treating B-cell leukemia in
children and young adults. However, their effectiveness in treating B-cell lymphomas has …

Cancer metastasis accounts for a majority of cancer-related deaths worldwide. Metastasis
occurs when the primary tumor sheds cells into the blood and lymphatic circulation, thereby …

Oncolytic virotherapy, utilizing genetically modified viruses to combat cancer and trigger anti-
cancer immune responses, has garnered significant attention in recent years. In our …

Oncology research has focused extensively on estrogen hormones and their function in
breast cancer proliferation. Mathematical modeling is essential for the analysis and …

This study aimed to investigate the predictive value of coagulation, thromboelastography,
stress response, and immune function indicators for the occurrence of deep venous …