Homologous recombination (HR) is required for accurate chromosome segregation during
the first meiotic division and constitutes a key repair and tolerance pathway for complex DNA …

DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role
in maintaining genomic stability. The specificity of MMR is primarily for base-base …

The concept of mismatch repair (MMR) was formulated independently in 1964 to explain the
removal of brominated nucleotides from DNA as well as gene conversion during genetic …

▪ Abstract Meiotic chromosomes have been studied for many years, in part because of the
fundamental life processes they represent, but also because meiosis involves the formation …

Mismatch repair stabilizes the cellular genome by correcting DNA replication errors and by
blocking recombination events between divergent DNA sequences. The reaction …

Mutations are rare events, occurring spontaneously at a frequency of 1 per 109-1010 base
pairs per cell division. 1, 2 Nucleotide misincorporation during DNA synthesis yields …

DNA mismatch repair (MMR) is an important DNA repair pathway that plays critical roles in
DNA replication fidelity, mutation avoidance and genome stability, all of which contribute …

Although homologous recombination and DNA repair phenomena in bacteria were initially
extensively studied without regard to any relationship between the two, it is now appreciated …

Like their nuclear counterpart, the plastid and mitochondrial genomes of plants have to be
faithfully replicated and repaired to ensure the normal functioning of the plant. Inability to …

Mice that are deficient in either the Pms2 or Msh2 DNA mismatch repair genes have
microsatellite instability and a predisposition to tumours. Interestingly, Pms2–deficient males …