Eosinophils from A to Z

L Gigon, T Fettrelet, S Yousefi, D Simon, HU Simon - Allergy, 2023 - Wiley Online Library
Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …

Cytokines in inflammatory bowel diseases–update 2020

M Leppkes, MF Neurath - Pharmacological Research, 2020 - Elsevier
Abstract Inflammatory Bowel Diseases (IBD), namely Crohn's Disease and Ulcerative Colitis,
cause a significant disease burden in modern civilization. Ever since the introduction of anti …

[HTML][HTML] The role of saliva in tick feeding

IMB Francischetti, A Sa-Nunes, BJ Mans… - … in bioscience: a …, 2009 - ncbi.nlm.nih.gov
When attempting to feed on their hosts, ticks face the problem of host hemostasis (the
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …

Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with …

S Kopetz, PM Hoff, JS Morris, RA Wolff… - Journal of clinical …, 2010 - ascopubs.org
Purpose We investigated the efficacy of fluorouracil (FU), leucovorin, irinotecan, and
bevacizumab (FOLFIRI+ B) in a phase II trial in patients previously untreated for metastatic …

Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells

L Jiang, Q Huang, S Zhang, Q Zhang, J Chang, X Qiu… - BMC cancer, 2010 - Springer
Abstract Background Two mature microRNAs (miRNAs), hsa-miR-125a-3p and hsa-miR-
125a-5p (collectively referred to as hsa-miR-125a-3p/5p), are derived from 3'and 5'ends of …

Eosinophil accumulation predicts response to melanoma treatment with immune checkpoint inhibitors

SCS Simon, X Hu, J Panten, M Grees, S Renders… - …, 2020 - Taylor & Francis
Eosinophils have been identified as a prognostic marker in immunotherapy of melanoma
and suggested to contribute to anti-tumor host defense. However, the influence of immune …

Regulation of cellular processes by interleukin‐16 in homeostasis and cancer

J Richmond, M Tuzova, W Cruikshank… - Journal of cellular …, 2014 - Wiley Online Library
Abstract Interleukin‐16 (IL‐16) is generated as a precursor molecule that is cleaved by
caspase‐3 to produce a pro‐IL‐16 molecule that functions as a regulator of T cell growth …

Pathogenesis and classification of eosinophil disorders: a review of recent developments in the field

P Valent, GJ Gleich, A Reiter, F Roufosse… - Expert review of …, 2012 - Taylor & Francis
Eosinophils and their products play an essential role in the pathogenesis of various reactive
and neoplastic disorders. Depending on the underlying disease, molecular defect and …

lnterleukin-16: the ins and outs of regulating T-cell activation

W Cruikshank, F Little - Critical Reviews™ in Immunology, 2008 - dl.begellhouse.com
ABSTRACT Intcrleukin-16 (IL-16) was originally identified in 1980 as the first-described T-
cell chemoattractant. Since that time, the protein has been cloned, sequenced, and …

IL-16 is critical for Tropheryma whipplei replication in Whipple's disease

B Desnues, D Raoult, JL Mege - The Journal of Immunology, 2005 - journals.aai.org
Whipple's disease (WD) is a rare systemic disease caused by Tropheryma whipplei. We
showed that T. whipplei was eliminated by human monocytes but replicated in monocyte …