Notch signalling: multifaceted role in development and disease

N Sachan, V Sharma, M Mutsuddi… - The FEBS …, 2024 - Wiley Online Library
Notch pathway is an evolutionarily conserved signalling system that operates to influence an
astonishing array of cell fate decisions in different developmental contexts. Notch signalling …

Ontogenesis of lateralization

O Güntürkün, S Ocklenburg - Neuron, 2017 - cell.com
The brains of humans and other animals are asymmetrically organized, but we still know
little about the ontogenetic and neural fundaments of lateralizations. Here, we review the …

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

LA Timmerman, J Grego-Bessa, A Raya… - Genes & …, 2004 - genesdev.cshlp.org
Epithelial-to-mesenchymal transition (EMT) is fundamental to both embryogenesis and
tumor metastasis. The Notch intercellular signaling pathway regulates cell fate determination …

[图书][B] The lateralized brain: The neuroscience and evolution of hemispheric asymmetries

S Ocklenburg, O Güntürkün - 2024 - books.google.com
The second edition of The Lateralized Brain provides for readers a volume detailing the
functional and structural differences between the left and right hemispheres of the brain …

Nodal signaling in vertebrate development

AF Schier - Annual review of cell and developmental biology, 2003 - annualreviews.org
▪ Abstract TGFß signals belonging to the Nodal family set up the embryonic axes, induce
mesoderm and endoderm, pattern the nervous system, and determine left-right asymmetry in …

Calcium at fertilization and in early development

M Whitaker - Physiological reviews, 2006 - journals.physiology.org
Fertilization calcium waves are introduced, and the evidence from which we can infer
general mechanisms of these waves is presented. The two main classes of hypotheses put …

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

LT Krebs, JR Shutter, K Tanigaki, T Honjo… - Genes & …, 2004 - genesdev.cshlp.org
The Notch signaling pathway is essential for embryonic vascular development in
vertebrates. Here we show that mouse embryos heterozygous for a targeted mutation in the …

[HTML][HTML] Tumor cell vasculogenic mimicry: from controversy to therapeutic promise

REB Seftor, AR Hess, EA Seftor, DA Kirschmann… - The American journal of …, 2012 - Elsevier
In 1999, The American Journal of Pathology published an article entitled “Vascular Channel
Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry,” by …

[HTML][HTML] Left–right asymmetry in embryonic development: a comprehensive review

M Levin - Mechanisms of development, 2005 - Elsevier
Embryonic morphogenesis occurs along three orthogonal axes. While the patterning of the
anterior–posterior and dorsal–ventral axes has been increasingly well characterized, the left …

[图书][B] Biological physics of the developing embryo

G Forgacs, SA Newman - 2005 - books.google.com
During development cells and tissues undergo changes in pattern and form that employ a
wider range of physical mechanisms than at any other time in an organism's life. This book …