Sickle cell disease (SCD) is an umbrella term for a group of life‐long debilitating autosomal
recessive disorders that are caused by a single‐point mutation (Glu→ Val) that results in …

Sickle cell disease (SCD) is the most common life-threatening monogenic disorder in the
world. The disease is highly prevalent in malaria endemic areas with over 75% of patients …

Sickle cell disease (SCD) is a common condition within sub-Saharan Africa and associated
with high under-5 mortality (U5M). The American Society of Hematology instituted the …

Background Sickle cell disease is highly prevalent in sub-Saharan Africa, where it accounts
for substantial morbidity and mortality. Newborn screening is paramount for early diagnosis …

Sickle cell disease (SCD) is an inherited monogenic disorder with high prevalence
throughout sub-Saharan Africa, the Mediterranean basin, the Middle East, and India …

In an effort to explore new knowledge and to develop meaningful collaborations for
improving child health, the First Pan African Workshop on Newborn Screening was …

Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy,
characterized by painful episodes, anemia, high risk of infection, and other acute and …

Sickle cell disease (SCD) is a life‐threatening disease requiring reliable early diagnosis. We
assessed the acceptability and diagnostic performances of two rapid diagnostic tests (RDTs) …

Objectives Given the fundamental role of newborn bloodspot screening (NBS) to enable
prompt diagnosis and optimal clinical management of individuals with sickle cell disease …

Sickle cell disease is caused by a single point mutation (Glu6Val) that promotes
polymerisation of haemoglobin S and sickling of erythrocytes. Inflammation, haemolysis …