Global patterns in excess body weight and the associated cancer burden

H Sung, RL Siegel, LA Torre… - CA: a cancer journal …, 2019 - Wiley Online Library
The prevalence of excess body weight and the associated cancer burden have been rising
over the past several decades globally. Between 1975 and 2016, the prevalence of excess …

[HTML][HTML] Obesity, diabetes, and increased cancer progression

DS Kim, PE Scherer - Diabetes & metabolism journal, 2021 - ncbi.nlm.nih.gov
Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …

[HTML][HTML] Advances in the prevention and treatment of obesity-driven effects in breast cancers

K Chen, J Zhang, NM Beeraka, C Tang… - Frontiers in …, 2022 - frontiersin.org
Obesity and associated chronic inflammation were shown to facilitate breast cancer (BC)
growth and metastasis. Leptin, adiponectin, estrogen, and several pro-inflammatory …

Abdominal obesity, adipokines and non-communicable diseases

D Dhawan, S Sharma - The Journal of steroid biochemistry and molecular …, 2020 - Elsevier
Abdominal obesity may be defined as excess deposits of fat in the abdominal region. It is a
common health condition seen in South Asians and is positively related to non …

Adenomyosis: mechanisms and pathogenesis

J Zhai, S Vannuccini, F Petraglia… - Seminars in …, 2020 - thieme-connect.com
Adenomyosis is a common disorder of the uterus, and is associated with an enlarged uterus,
heavy menstrual bleeding (HMB), pelvic pain, and infertility. It is characterized by …

Obesity and cancer—mechanisms underlying tumour progression and recurrence

J Park, TS Morley, M Kim, DJ Clegg… - Nature Reviews …, 2014 - nature.com
Over the past several years, the field of cancer research has directed increased interest
towards subsets of obesity-associated tumours, which include mammary, renal …

[HTML][HTML] Sex, body mass index, and dietary fiber intake influence the human gut microbiome

C Dominianni, R Sinha, JJ Goedert, Z Pei, L Yang… - PloS one, 2015 - journals.plos.org
Increasing evidence suggests that the composition of the human gut microbiome is
important in the etiology of human diseases; however, the personal factors that influence the …

Is there a causal relationship between obesity and puberty?

T Reinehr, CL Roth - The Lancet Child & Adolescent Health, 2019 - thelancet.com
The onset of puberty in adolescents and whether it is related to obesity is an ongoing topic
for debate. Epidemiological cross-sectional and longitudinal studies show a shift towards …

Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer

JJ Kim, T Kurita, SE Bulun - Endocrine reviews, 2013 - academic.oup.com
Progesterone receptor (PR) mediates the actions of the ovarian steroid progesterone, which
together with estradiol regulates gonadotropin secretion, prepares the endometrium for …

[HTML][HTML] Obesity, leptin and breast cancer: epidemiological evidence and proposed mechanisms

S Andò, L Gelsomino, S Panza, C Giordano… - Cancers, 2019 - mdpi.com
The prevalence of obesity has been steadily increasing over the past few decades in several
developed and developing countries, with resultant hazardous health implications …