[HTML][HTML] Reassessing the host defense peptide landscape

EF Haney, SK Straus, REW Hancock - Frontiers in chemistry, 2019 - frontiersin.org
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

Nanotechnology based anti‐infectives to fight microbial intrusions

M Rai, AP Ingle, S Gaikwad, I Gupta… - Journal of Applied …, 2016 - academic.oup.com
With the rise in human population across the globe especially in developing countries, the
incidence of microbial infections are increasing with greater pace. On the other hand …

Combating drug-resistant fungi with novel imperfectly amphipathic palindromic peptides

J Wang, S Chou, Z Yang, Y Yang, Z Wang… - Journal of medicinal …, 2018 - ACS Publications
Antimicrobial peptides are an important weapon against invading pathogens and are
potential candidates as novel antibacterial agents, but their antifungal activities are not fully …

Characterization of simplified nonapeptides with broad-spectrum antimicrobial activities as potential food preservatives, and their antibacterial mechanism

Z Yang, Y Wei, W Wu, L Zhang, J Wang, A Shan - Food & Function, 2023 - pubs.rsc.org
Antimicrobial peptides (AMPs) have attracted attention in the field of food preservatives due
to their favorable biosafety and potential antimicrobial activity. However, high synthetic cost …

Aggregation-induced emission probe for study of the bactericidal mechanism of antimicrobial peptides

J Chen, M Gao, L Wang, S Li, J He, A Qin… - … applied materials & …, 2018 - ACS Publications
Multidrug resistant bacterial infection has become one of the most serious threats to human
health. Antimicrobial peptides (AMPs) have been identified as potential alternatives to …

Short, mirror-symmetric antimicrobial peptides centered on “RRR” have broad-spectrum antibacterial activity with low drug resistance and toxicity

F Zhang, P Yang, W Mao, C Zhong, J Zhang, L Chang… - Acta Biomaterialia, 2022 - Elsevier
The increasingly severe bacterial resistance worldwide pushes people to discover and
design potential antibacterial drugs unavoidably. In this work, a series of short, mirror …

New antimicrobial peptides with repeating unit against multidrug-resistant bacteria

C Zhong, F Zhang, J Yao, Y Zhu, N Zhu… - ACS Infectious …, 2021 - ACS Publications
With the aim of tackling the increasingly serious antimicrobial resistance and improving the
clinical potential of AMPs, a facile de novo strategy was adopted in this study, and a series of …

New insights into the mode of action of the lantibiotic salivaricin B

A Barbour, J Tagg, OK Abou-Zied, K Philip - Scientific reports, 2016 - nature.com
Salivaricin B is a 25 amino acid polycyclic peptide belonging to the type AII lantibiotics and
first shown to be produced by Streptococcus salivarius. In this study we describe the …

Modified histidine containing amphipathic ultrashort antifungal peptide, His [2-p-(n-butyl) phenyl]-Trp-Arg-OMe exhibits potent anticryptococcal activity

KK Sharma, R Ravi, IK Maurya, A Kapadia… - European Journal of …, 2021 - Elsevier
In pursuit of ultrashort peptide-based antifungals, a new structural class, His (2-aryl)-Trp-Arg
is reported. Structural changes were investigated on His-Trp-Arg scaffold to demonstrate the …

HHC-36 antimicrobial peptide loading on silk fibroin (SF)/hydroxyapatite (HA) nanofibrous-coated titanium for the enhancement of osteoblast and bactericidal …

N Abbasizadeh, AH Rezayan… - … Journal of Polymeric …, 2020 - Taylor & Francis
Improving osseointegration together with preventing infections are the main challenges of
using titanium-based implants in joint replacement surgeries. In this study, a hybrid …