Recurrent pregnancy loss is a distressing pregnancy disorder experienced by~ 2.5% of
women trying to conceive. Recurrent pregnancy loss is defined as the failure of two or more …

Accumulating evidence from preclinical and clinical studies indicates that maternal
psychosocial stress and anxiety during pregnancy adversely affect child outcomes …

OBJECTIVE: To create a genomic tool composed of a customized microarray and a
bioinformatic predictor for endometrial dating and to detect pathologies of endometrial …

Implantation of the embryo into the uterine endometrium is one of the most finely-regulated
processes that leads to the establishment of a successful pregnancy. A plethora of factors …

All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …

Implantation failure and inadequate placental development are important contributors to
infertility, recurrent miscarriage, and other pregnancy-related problems in women. Better …

During pregnancy, immune activity is tightly regulated so that antimicrobial protection of the
mother and fetus is balanced with the need for immune tolerance to prevent fetal rejection. In …

All mammalian uteri contain glands in the endometrium that synthesize or transport and
secrete substances essential for survival and development of the conceptus (embryo/fetus …

Interleukin-8 (IL8/CXCL8) is present in decidua and trophoblast, which also expresses the
IL8 receptors, CXCR1 and CXCR2. IL8 was shown to stimulate trophoblast migration. Matrix …

Cytokines and other immune mediators are secreted by cells of the immune system during
immune responses and as a means of communication. While the functions of these …