Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …

In response to stress signal, nuclear factor‐erythroid 2‐related factor 2 (Nrf2) induces the
expression of target genes involved in antioxidant defense and detoxification. Nrf2 activity is …

Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …

Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …

One of the major causes of long-term disability and mortality is ischemic stroke that enjoys
limited treatment approaches. On the one hand, oxidative stress, induced by excessive …

Ferroptosis is a form of non-apoptotic cell death caused by iron-dependent peroxidation of
lipids. It contributes to ischemic stroke-induced neuronal damage. Elabela (ELA), a novel …

Ischemic stroke, a cerebrovascular disease worldwide, triggers a cascade of
pathophysiological events, including blood‐brain barrier (BBB) breakdown. Brain …

Astrocytes, as the most abundant glial cells in the central nervous system, are tightly
integrated into neural networks and participate in numerous aspects of brain physiology and …

Ischemic stroke occurs when the arteries supplying blood to the brain are narrowed or
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …