[HTML][HTML] Immune evasion by cancer stem cells

H Tsuchiya, G Shiota - Regenerative Therapy, 2021 - Elsevier
Tumor immunity represents a new avenue for cancer therapy. Immune checkpoint inhibitors
have successfully improved outcomes in several tumor types. In addition, currently, immune …

3D bioprinting of tumor models for cancer research

Y Kang, P Datta, S Shanmughapriya… - ACS Applied Bio …, 2020 - ACS Publications
The exact mechanistic understanding of cancer metastasis continues to be unknown,
although it is a major cause of death worldwide. Along with the tumor mass, the tumor …

Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs

CH Lee, CC Yu, BY Wang, WW Chang - Oncotarget, 2015 - pmc.ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are a sub-population of cells within cancer tissues with tumor
initiation, drug resistance and metastasis properties. CSCs also have been considered as …

Cancer stem cells: regulation programs, immunological properties and immunotherapy

D Zhang, DG Tang, K Rycaj - Seminars in cancer biology, 2018 - Elsevier
It is becoming increasingly clear that virtually all types of human cancers harbor a small
population of stem-like cancer cells (ie, cancer stem cells, CSCs). These CSCs preexist in …

[HTML][HTML] Immunotherapy for targeting cancer stem cells in hepatocellular carcinoma

X Dai, Y Guo, Y Hu, X Bao, X Zhu, Q Fu, H Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
The rapid development and remarkable success of checkpoint inhibitors have provided
significant breakthroughs in cancer treatment, including hepatocellular carcinoma (HCC) …

Meet me halfway: Are in vitro 3D cancer models on the way to replace in vivo models for nanomedicine development?

S Pozzi, A Scomparin, SI Dangoor, DR Ajamil… - Advanced Drug Delivery …, 2021 - Elsevier
The complexity and diversity of the biochemical processes that occur during tumorigenesis
and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two …

Immune responses to human cancer stem‐like cells/cancer‐initiating cells

Y Hirohashi, T Torigoe, T Tsukahara… - Cancer …, 2016 - Wiley Online Library
Cancer stem‐like cells (CSC)/cancer‐initiating cells (CIC) are defined as minor
subpopulations of cancer cells that are endowed with properties of higher tumor‐initiating …

Microfluidic models for adoptive cell-mediated cancer immunotherapies

G Adriani, A Pavesi, AT Tan, A Bertoletti, JP Thiery… - Drug Discovery …, 2016 - Elsevier
Highlights•3D microfluidic tumour models are effective in screening for T cell therapeutic
strategies.•3D microfluidics can decrease the cost and time for optimising T cell …

Biomedical applications of non-small cell lung cancer spheroids

JM Rozenberg, GI Filkov, AV Trofimenko… - Frontiers in …, 2021 - frontiersin.org
Lung malignancies accounted for 11% of cancers worldwide in 2020 and remained the
leading cause of cancer deaths. About 80% of lung cancers belong to non-small cell lung …

The cross talk between cancer stem cells/cancer initiating cells and tumor microenvironment: the missing piece of the puzzle for the efficient targeting of these cells …

S Ravindran, S Rasool, C Maccalli - Cancer Microenvironment, 2019 - Springer
Abstract Cancer Stem Cells/Cancer Initiating Cells (CSCs/CICs) is a rare sub-population
within a tumor that is responsible for tumor formation, progression and resistance to …