[HTML][HTML] Impact of radiotherapy boost on pathological complete response in patients with locally advanced rectal cancer: a systematic review and meta-analysis
JPM Burbach, AM den Harder, M Intven… - Radiotherapy and …, 2014 - Elsevier
Purpose We conducted a systematic review and meta-analysis to quantify the pathological
complete response (pCR) rate after preoperative (chemo) radiation with doses of⩾ 60 Gy in …
complete response (pCR) rate after preoperative (chemo) radiation with doses of⩾ 60 Gy in …
Organ preservation in rectal cancer: have all questions been answered?
CAM Marijnen - The lancet oncology, 2015 - thelancet.com
Improved treatment strategies have eliminated local control as the major problem in rectal
cancer. With increasing awareness of long-term toxic effects in survivors of rectal cancer …
cancer. With increasing awareness of long-term toxic effects in survivors of rectal cancer …
No benefit of adjuvant Fluorouracil Leucovorin chemotherapy after neoadjuvant chemoradiotherapy in locally advanced cancer of the rectum (LARC): Long term …
A Sainato, VCL Nunzia, V Valentini, A De Paoli… - Radiotherapy and …, 2014 - Elsevier
Background and purpose To evaluate the effect of adjuvant chemotherapy (ACT) in locally
advanced rectal cancer (LARC) after neoadjuvant chemoradiation (NACT-RT). The study …
advanced rectal cancer (LARC) after neoadjuvant chemoradiation (NACT-RT). The study …
A deep learning‐based autosegmentation of rectal tumors in MR images
Purpose Manual contouring of gross tumor volumes (GTV) is a crucial and time‐consuming
process in rectum cancer radiotherapy. This study aims to develop a simple deep learning …
process in rectum cancer radiotherapy. This study aims to develop a simple deep learning …
[HTML][HTML] Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species
Auranofin (AF) is an anti-arthritic drug considered for combined chemotherapy due to its
ability to impair the redox homeostasis in tumor cells. In this study, we asked whether AF …
ability to impair the redox homeostasis in tumor cells. In this study, we asked whether AF …
Late gastrointestinal toxicity after radiotherapy for rectal cancer: a systematic review
A Sipaviciute, E Sileika, A Burneckis… - International Journal of …, 2020 - Springer
Purpose Although the multimodal cancer treatment techniques have greatly improved over
the years, irradiation-induced late gastrointestinal toxicity remains a great concern as it may …
the years, irradiation-induced late gastrointestinal toxicity remains a great concern as it may …
Considering patient values and treatment preferences enhances patient involvement in rectal cancer treatment decision making
M Kunneman, CAM Marijnen… - Radiotherapy and …, 2015 - Elsevier
Background The shared decision making (SDM) model states that patients' values and
preferences should be clarified to choose a strategy that best fits the patient. This study …
preferences should be clarified to choose a strategy that best fits the patient. This study …
A comparative analysis between radiation dose intensification and conventional fractionation in neoadjuvant locally advanced rectal cancer: A monocentric …
E Bertocchi, G Barugola, L Nicosia, R Mazzola… - La radiologia …, 2020 - Springer
Purpose The potential role of neoadjuvant radiation dose intensification in locally advanced
rectal cancer (LARC) is still largely debated. In the present study, a comparative analysis …
rectal cancer (LARC) is still largely debated. In the present study, a comparative analysis …
The role of simultaneous integrated boost in locally advanced rectal cancer patients with positive lateral pelvic lymph nodes
E Meldolesi, G Chiloiro, R Giannini, R Menghi… - Cancers, 2022 - mdpi.com
Simple Summary Around 15% of locally advanced rectal cancer patients have positive
lateral pelvic lymph-nodes at diagnosis, with a worse prognosis due to the high incidence of …
lateral pelvic lymph-nodes at diagnosis, with a worse prognosis due to the high incidence of …
Neoadjuvant radiotherapy dose escalation in locally advanced rectal cancer: a systematic review and meta-analysis of modern treatment approaches and outcomes
N Hearn, D Atwell, K Cahill, J Elks, D Vignarajah… - Clinical Oncology, 2021 - Elsevier
Aims Improving pathological complete response (pCR) rates after neoadjuvant
chemoradiotherapy for locally advanced rectal cancer may facilitate surgery-sparing …
chemoradiotherapy for locally advanced rectal cancer may facilitate surgery-sparing …