FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug resistance …, 2020 - Elsevier
In December 2019, a novel SARS-CoV-2 coronavirus emerged, causing an outbreak of life-
threatening pneumonia in the Hubei province, China, and has now spread worldwide …

Biological and pharmacological roles of m6A modifications in cancer drug resistance

Z Liu, H Zou, Q Dang, H Xu, L Liu, Y Zhang, J Lv, H Li… - Molecular Cancer, 2022 - Springer
Cancer drug resistance represents the main obstacle in cancer treatment. Drug-resistant
cancers exhibit complex molecular mechanisms to hit back therapy under pharmacological …

St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death

B Kleemann, B Loos, TJ Scriba, D Lang, LM Davids - PloS one, 2014 - journals.plos.org
Hypericin, an extract from St John's Wort (Hypericum perforatum L.), is a promising
photosensitizer in the context of clinical photodynamic therapy due to its excellent …

Engaging the lysosome and lysosome-dependent cell death in cancer

AL Berg, A Rowson-Hodel, MR Wheeler… - Exon …, 2022 - exonpublications.com
While patient-specific targeting of cellular growth and viability pathways dominates current
approaches in anti cancer therapeutics development, appreciation for the strategy of …

Transcriptome Analysis Reveals the Involvement of Mitophagy and Peroxisome in the Resistance to QoIs in Corynespora cassiicola

B Sun, R Zhou, G Zhu, X Xie, A Chai, L Li, T Fan, B Li… - Microorganisms, 2023 - mdpi.com
Quinone outside inhibitor fungicides (QoIs) are crucial fungicides for controlling plant
diseases, but resistance, mainly caused by G143A, has been widely reported with the high …

Photodynamic therapy of multidrug resistant leukemic murine cells by 3, 6-bis (alkylthiourea) acridine hydrochlorides.

H Paulikova, A Cisáriková, Z Bačová, L Janovec… - …, 2021 - search.ebscohost.com
Efforts to overcome multidrug resistance in cancer have led to the development of several
novel strategies including photodynamic therapy (PDT). PDT is based on the use of …