Gut microbiota and immune system interactions

JY Yoo, M Groer, SVO Dutra, A Sarkar, DI McSkimming - Microorganisms, 2020 - mdpi.com
Dynamic interactions between gut microbiota and a host's innate and adaptive immune
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …

Gut microbiota, leaky gut, and autoimmune diseases

A Christovich, XM Luo - Frontiers in immunology, 2022 - frontiersin.org
With the rising prevalence of autoimmune diseases, the role of the environment, specifically
the gut microbiota, in disease development has grown to be a major area of study. Recent …

Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

N Tajik, M Frech, O Schulz, F Schälter, S Lucas… - Nature …, 2020 - nature.com
Gut microbial dysbiosis is associated with the development of autoimmune disease, but the
mechanisms by which microbial dysbiosis affects the transition from asymptomatic …

Aspects of gut microbiota and immune system interactions in infectious diseases, immunopathology, and cancer

V Lazar, LM Ditu, GG Pircalabioru, I Gheorghe… - Frontiers in …, 2018 - frontiersin.org
The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea,
and protozoans, bringing to the host organism a dowry of cells and genes more numerous …

Role of Lactobacillus reuteri in Human Health and Diseases

Q Mu, VJ Tavella, XM Luo - Frontiers in microbiology, 2018 - frontiersin.org
Lactobacillus reuteri (L. reuteri) is a well-studied probiotic bacterium that can colonize a
large number of mammals. In humans, L. reuteri is found in different body sites, including the …

New insights into the immunopathogenesis of systemic lupus erythematosus

GC Tsokos, MS Lo, PC Reis, KE Sullivan - Nature Reviews …, 2016 - nature.com
The aetiology of systemic lupus erythematosus (SLE) is multifactorial, and includes
contributions from the environment, stochastic factors, and genetic susceptibility. Great gains …

Microbial dysbiosis in the gut drives systemic autoimmune diseases

WK Mousa, F Chehadeh, S Husband - Frontiers in immunology, 2022 - frontiersin.org
Trillions of microbes survive and thrive inside the human body. These tiny creatures are
crucial to the development and maturation of our immune system and to maintain gut …

The role of the gut microbiome in systemic inflammatory disease

JC Clemente, J Manasson, JU Scher - Bmj, 2018 - bmj.com
The role of the gut microbiome in models of inflammatory and autoimmune disease is now
well characterized. Renewed interest in the human microbiome and its metabolites, as well …

The oral microbiota is modified by systemic diseases

DT Graves, JD Corrêa, TA Silva - Journal of dental research, 2019 - journals.sagepub.com
Periodontal diseases are initiated by bacteria that accumulate in a biofilm on the tooth
surface and affect the adjacent periodontal tissue. Systemic diseases such as diabetes …

Crosstalk between gut microbiota and innate immunity and its implication in autoimmune diseases

Y Jiao, L Wu, ND Huntington, X Zhang - Frontiers in immunology, 2020 - frontiersin.org
The emerging concept of microbiota contributing to local mucosal homeostasis has fueled
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …