Coined three decades ago, the term aptamer and directed evolution have now reached their
maturity. The concept that nucleic acid could modulate the activity of target protein as ligand …

Breast carcinomas repeat their number and grow exponentially making it extremely frequent
malignancy among women. Approximately, 70–80% of early diagnosed or non-metastatic …

Aptamers are single-stranded DNA or RNA oligonucleotides that can selectively bind to a
specific target. They are generally obtained by SELEX, but the procedure is challenging and …

Liver plays a critical role in drug metabolism and nowadays multi-cellular culture systems
aiming at imitating liver-specific morphology and functionality are advancing robustly …

Nucleic-acid aptamers consisting in single-stranded DNA oligonucleotides emerged as very
promising biorecognition elements for electrochemical biosensors applied in various fields …

Food-borne pathogens pose significant risks to public health and food safety, necessitating
the development of rapid, sensitive, and multiplex detection techniques. Biosensor is one of …

Aptamers, as recognition molecules, play an important role in the field of detection and
control. Screening is the key procedure to obtain aptamers. Improving the aptamer …

During the coronavirus disease 2019 (COVID-19) pandemic, a novel multisystem
inflammatory syndrome in children (MIS-C) has been reported worldwide since the first …

Aptamers are single-stranded oligonucleotide sequences capable of binding to specific
ligands with high affinity. In this manner, they are like antibodies but have advantages such …

Brucellae are Gram-negative, aerobic, non-motile coccobacilli causing brucellosis in man
and animals. The disease is one of the most significant yet neglected global zoonoses …