Homology modeling in drug discovery: Overview, current applications, and future perspectives

MT Muhammed, E Aki‐Yalcin - Chemical biology & drug design, 2019 - Wiley Online Library
Homology modeling is one of the computational structure prediction methods that are used
to determine protein 3D structure from its amino acid sequence. It is considered to be the …

[HTML][HTML] Homology modeling a fast tool for drug discovery: current perspectives

VK Vyas, RD Ukawala, M Ghate… - Indian journal of …, 2012 - ncbi.nlm.nih.gov
Major goal of structural biology involve formation of protein-ligand complexes; in which the
protein molecules act energetically in the course of binding. Therefore, perceptive of protein …

RETRACTED ARTICLE: Antiviral Activity of Chitosan Nanoparticles Encapsulating Curcumin Against Hepatitis C Virus Genotype 4a in Human Hepatoma Cell Lines

SA Loutfy, MH Elberry, KY Farroh… - International journal …, 2020 - Taylor & Francis
Loutfy SA, Elberry MH, Farroh KY, et al. Int J Nanomedicine. 2020; 15: 2699–2715. The
Editor and Publisher of International Journal of Nanomedicine wish to retract the published …

Biogenic Synthesis of Copper Oxide Nanoparticles from Aloe vera: Antibacterial Activity, Molecular Docking, and Photocatalytic Dye Degradation

S Jabeen, VU Siddiqui, S Bala, N Mishra, A Mishra… - ACS …, 2024 - ACS Publications
Green synthesis methods offer a cost-effective and environmentally friendly approach to
producing nanoparticles (NPs), particularly metal-based oxides. This study explores the …

Integrated approach to structure-based enzymatic drug design: molecular modeling, spectroscopy, and experimental bioactivity

B Honarparvar, T Govender, GEM Maguire… - Chemical …, 2014 - ACS Publications
Analysis of the literature involving computational modeling of diseases and drug design with
the aid of experimental spectroscopic techniques reveals that this specific combination of …

The cryoprotectant effect of xylooligosaccharides on denaturation of peeled shrimp (Litopenaeus vannamei) protein during frozen storage

B Zhang, G Hao, H Cao, H Tang, Y Zhang, S Deng - Food Hydrocolloids, 2018 - Elsevier
The cryoprotective effects of xylooligosaccharides on peeled whiteleg shrimp were
investigated and compared with sodium pyrophosphate treatment during frozen storage …

Ten quick tips for homology modeling of high-resolution protein 3D structures

Y Haddad, V Adam, Z Heger - PLoS computational biology, 2020 - journals.plos.org
Author summary The purpose of this quick guide is to help new modelers who have little or
no background in comparative modeling yet are keen to produce high-resolution protein 3D …

Application of data mining in bioinformatics

K Raza - arXiv preprint arXiv:1205.1125, 2012 - arxiv.org
This article highlights some of the basic concepts of bioinformatics and data mining. The
major research areas of bioinformatics are highlighted. The application of data mining in the …

Berberine bridge enzyme-like oxidase-catalysed double bond isomerization acts as the pathway switch in cytochalasin synthesis

JM Zhang, X Liu, Q Wei, C Ma, D Li, Y Zou - Nature Communications, 2022 - nature.com
Cytochalasans (CYTs), as well as their polycyclic (pcCYTs) and polymerized (meCYTs)
derivatives, constitute one of the largest families of fungal polyketide-nonribosomal peptide …

Cryoprotective roles of trehalose and alginate oligosaccharides during frozen storage of peeled shrimp (Litopenaeus vannamei)

B Zhang, H Wu, H Yang, X Xiang, H Li, S Deng - Food chemistry, 2017 - Elsevier
Cryoprotective saccharides are widely accepted additives that reduce thawing loss, maintain
texture, and retard protein denaturation in the frozen seafood. The present study aimed to …