Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review

MS More, PG Joshi, YK Mishra, PK Khanna - Materials Today Chemistry, 2019 - Elsevier
Schiff bases are versatile organic compounds which are widely used and synthesized by
condensation reaction of different amino compound with aldehydes or ketones known as …

Metal compounds against neglected tropical diseases

YC Ong, S Roy, PC Andrews, G Gasser - Chemical reviews, 2018 - ACS Publications
Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

Molecular basis of antimony treatment in leishmaniasis

P Baiocco, G Colotti, S Franceschini… - Journal of medicinal …, 2009 - ACS Publications
Leishmaniasis is a disease that affects 2 million people and kills 70000 persons every year.
It is caused by Leishmania species, which are human protozoan parasites of the …

Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

M Navarro, C Gabbiani, L Messori, D Gambino - Drug discovery today, 2010 - Elsevier
Tropical diseases today constitute a major health problem and a big challenge for drug
discovery. Because of the limited arsenal of effective antiparasitic agents and the frequent …

Thiosemicarbazone metal complexes: from structure to activity

G Pelosi - The Open Crystallography Journal, 2010 - benthamopen.com
Thiosemicarbazones and their metal complexes are compounds that possess antitumor,
antibacterial, antifungal and antiviral properties. For the foremost majority of cases the …

A novel palladium (II) antitumor agent: Synthesis, characterization, DFT perspective, CT-DNA and BSA interaction studies via in-vitro and in-silico approaches

M Feizi-Dehnayebi, E Dehghanian… - … Acta Part A: Molecular …, 2021 - Elsevier
Since numerous people annually pass away due to cancer, research in this field is essential.
Thus a newly made and water like palladium (II) complex of formula [Pd (phen)(acac)] NO 3 …

Heterocyclic N-oxides-an emerging class of therapeutic agents

AM Mfuh, OV Larionov - Current medicinal chemistry, 2015 - ingentaconnect.com
Heterocyclic N-oxides have emerged as potent compounds with anticancer, antibacterial,
antihypertensive, antiparasitic, anti-HIV, anti-inflammatory, herbicidal, neuroprotective, and …

Neglected Tropical Diseases: Multi-Target-Directed Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania

A Cavalli, ML Bolognesi - Journal of Medicinal Chemistry, 2009 - ACS Publications
“We have never had such a sophisticated arsenal of technologies for treating diseases, yet
the gap in health outcomes keep getting wider. This is unacceptable.” This claim was made …

Gold complexes as potential anti-parasitic agents

M Navarro - Coordination Chemistry Reviews, 2009 - Elsevier
The medical uses of gold have a long history; rheumatoid arthritis is currently treated with
gold-based drugs and there is increasing interest in the application of gold complexes as …

Potentiality of vanadium compounds as anti-parasitic agents

D Gambino - Coordination Chemistry Reviews, 2011 - Elsevier
Research efforts on the medicinal chemistry of vanadium have been mainly focused whether
on improving biodistribution and tolerability of the vanadium insulin-enhancing core or on …