Fluorogenic reactions in chemical biology: seeing chemistry in cells

Y Chen, H Jiang, T Hao, N Zhang, M Li… - … & Biomedical Imaging, 2023 - ACS Publications
Among the recent development of click chemistry and bioorthogonal chemistry, fluorogenic
reactions occupy a unique place in that fluorescence is generated from nonfluorescent …

Enzyme engineering for functional lipids synthesis: recent advance and perspective

A Guan, Y Hou, R Yang, J Qin - Bioresources and Bioprocessing, 2024 - Springer
Functional lipids, primarily derived through the modification of natural lipids by various
processes, are widely acknowledged for their potential to impart health benefits. In contrast …

Bioorthogonally activated probes for precise fluorescence imaging

Y Fu, X Zhang, L Wu, M Wu, TD James… - Chemical Society …, 2024 - pubs.rsc.org
Over the past two decades, bioorthogonal chemistry has undergone a remarkable
development, challenging traditional assumptions in biology and medicine. Recent …

Toolbox for the structure-guided evolution of ferulic acid decarboxylase (FDC)

H Duță, A Filip, LC Nagy, EZA Nagy, R Tőtős… - Scientific Reports, 2022 - nature.com
The interest towards ferulic acid decarboxylase (FDC), piqued by the enzyme's unique 1, 3-
dipolar cycloaddition mechanism and its atypic prFMN cofactor, provided several …

A unique P450 peroxygenase system facilitated by a dual-functional small molecule: Concept, application, and perspective

S Di, S Fan, F Jiang, Z Cong - Antioxidants, 2022 - mdpi.com
Cytochrome P450 monooxygenases (P450s) are promising versatile oxidative biocatalysts.
However, the practical use of P450s in vitro is limited by their dependence on the co-enzyme …

[HTML][HTML] Biocatalytic conversion of fatty acids into drop-in biofuels: Towards sustainable energy sources

P Santner, SN Chanquia, N Petrovai, FV Benfeldt… - EFB Bioeconomy …, 2023 - Elsevier
Intensifying effects of global warming necessitates swift solutions for decarbonization. A big
source for the increasing atmospheric CO 2 is burning of transportation fuels. Although …

Elucidating the Enzymatic Mechanism of Dihydrocoumarin Degradation: Insight into the Functional Evolution of Methyl-Parathion Hydrolase from QM/MM and MM MD …

Y Fu, J Yu, F Fan, B Wang, Z Cao - The Journal of Physical …, 2024 - ACS Publications
Methyl-parathion hydrolase (MPH), which evolved from dihydrocoumarin hydrolase, offers
one of the most efficient enzymes for the hydrolysis of methyl-parathion. Interestingly, the …

P450 fatty acid decarboxylase

Y Jiang, S Li - Methods in Enzymology, 2023 - Elsevier
P450 fatty acid decarboxylases are able to utilize hydrogen peroxide as the sole cofactor to
decarboxylate free fatty acids to produce α-olefins with abundant applications as drop-in …

Tuning the catalytic performances of a sucrose isomerase for production of isomaltulose with high concentration

F Zhang, F Cheng, DX Jia, Q Liu, ZQ Liu… - Applied Microbiology and …, 2022 - Springer
Obtaining a sucrose isomerase (SIase) with high catalytic performance is of great
importance in industrial production of isomaltulose (a reducing sugar). In order to obtain …

外消旋化合物生物催化去对称化研究进展

YM Su - Journal of Molecular Catalysis, 2021 - pure.bit.edu.cn
The biocatalytic desymmetrization of racemates of chiral compounds is the focus, difficulty
and hotspot in the field of biological and organic synthesis currently, and it is also an …