This chapter reviews how allosteric (heterotrophic) effectors and natural mutations impact
hemoglobin (Hb) primary physiological function of oxygen binding and transport. First, an …

Haemoglobin (Hb) is widely known as the iron-containing protein in blood that is essential
for O 2 transport in mammals. Less widely recognised is that erythrocyte Hb belongs to a …

" One impressive and compressive book.... This review would have to be book size to do full
justice to all the insights in this volume."—Journal of Metals Online Fully updated and …

We have designed programmable DNA-based nanoswitches whose closing/opening can be
triggered over specific different pH windows. These nanoswitches form an intramolecular …

Much of our understanding of human physiology, and of many aspects of pathology, has its
antecedents in laboratory and clinical studies of hemoglobin. Over the last century …

The discovery of the S‐shaped O2 equilibrium curve and the Bohr effect in 1904 stimulated
a fertile and continued research into respiratory functions of blood and allosteric …

Hemoglobin (Hb) constitutes a vital link between ambient O2 availability and aerobic
metabolism by transporting oxygen (O2) from the respiratory surfaces of the lungs or gills to …

La bioquímica es un campo de suma utilidad que nos despierta una enorme fascinación, sin
duda originada en nuestro interés por nosotros mismos. El bienestar humano, en particular …

The most recent refinement of the crystallographic structure of oxyhaemoglobin (oxyHb) was
completed in 1983, and differences between this real-space refined model and later R state …

Abstract Changes in intracellular pH regulate many cell behaviors, including proliferation,
migration, and transformation. However, our understanding of how physiological changes in …