Investigation of exon–intron gene structures is a non-trivial task due to enormous
expansions of the eukaryotic genomes, great variety of gene forms, and the imperfectness in …

Gene families often show degrees of differences in terms of exon–intron structures
depending on their distinct evolutionary histories. Comparative analysis of gene structures is …

SNPs located within the open reading frame of a gene that result in an alteration in the
amino acid sequence of the encoded protein [nonsynonymous SNPs (nsSNPs)] might …

Background Epigenetic regulators (histone acetyltransferases, methyltransferases,
chromatin-remodelling enzymes, etc) play a fundamental role in the control of gene …

Friend is a bioinformatics application designed for simultaneous analysis and visualization
of multiple structures and sequences of proteins and/or DNA/RNA. The application provides …

Proteins are the molecules of life which are involved in cellular processes. The functional
specificity of a protein is linked to its structure. A great section of bioinformatics deals with the …

We have developed ExDom, a unique database for the comparative analysis of the exon–
intron structures of 96 680 protein domains from seven eukaryotic organisms (Homo …

Search of interrelationships between the structural–functional protein organization and exon
structure of encoding gene provides insights into issues concerned with the function, origin …

Background Study of the relationship between the structural and functional organization of
proteins and their coding genes is necessary for an understanding of the evolution of …

The web application oriented on identification and visualization of protein regions encoded
by exons is presented. The Exon Visualiser can be used for visualisation on different levels …