Since the first publication on Somatic Mutation Theory of Aging (Szilárd, 1959), a great
volume of knowledge in the field has been accumulated. Here we attempted to organize the …

The development of clinical interventions that significantly improve human healthspan
requires robust markers of biological age as well as thoughtful therapeutic targets. To …

Molecular mechanisms of ovarian aging and female age-related fertility decline remain
unclear. We surveyed the single-cell transcriptomic landscape of ovaries from young and …

Telomere shortening to a critical length can trigger aging and shorter life spans in mice and
humans by a mechanism that involves induction of a persistent DNA damage response at …

In spite of a growing body of research and data, human ageing remains a poorly understood
process. Over 10 years ago we developed the Human Ageing Genomic Resources (HAGR) …

Abstract The Human Ageing Genomic Resources (HAGR, http://genomics. senescence. info)
is a freely available online collection of research databases and tools for the biology and …

Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …

Lifespan is a remarkably diverse trait ranging from a few days to several hundred years in
nature, but the mechanisms underlying the evolution of lifespan differences remain elusive …

Aging is a multifactorial process where deterioration of body functions is driven by stochastic
damage while counteracted by distinct genetically encoded repair systems. To better …

Mammals have evolved a remarkable diversity of ageing rates. Within the single order of
Rodentia, maximum lifespans range from 4 years in mice to 32 years in naked mole rats …