Cancer health disparities in racial/ethnic minorities in the United States

VA Zavala, PM Bracci, JM Carethers… - British journal of …, 2021 - nature.com
There are well-established disparities in cancer incidence and outcomes by race/ethnicity
that result from the interplay between structural, socioeconomic, socio-environmental …

Immune response and inflammation in cancer health disparities

M Kiely, B Lord, S Ambs - Trends in cancer, 2022 - cell.com
Cancer death rates vary among population groups. Underserved populations continue to
experience an excessive burden of lethal cancers that is largely explained by health-care …

Immune-related gene expression and cytokine secretion is reduced among African American colon cancer patients

J Paredes, J Zabaleta, J Garai, P Ji, S Imtiaz… - Frontiers in …, 2020 - frontiersin.org
Background: Colorectal cancer is the third most deadly cancer among African Americans
(AA). When compared to Caucasian Americans (CA), AA present with more advanced …

[HTML][HTML] Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics?

S Ahmad, H Ashktorab, H Brim… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Dysregulated interactions between host inflammation and gut microbiota over the course of
life increase the risk of colorectal cancer (CRC). While environmental factors and socio …

Role of IL-1β rs1143634 (+3954C>T) polymorphism in cancer risk: an updated meta-analysis and trial sequential analysis

S Jafrin, MA Aziz, MS Islam - Journal of International …, 2021 - journals.sagepub.com
Objective Oxidative stress caused by the pro-inflammatory cytokine interleukin (IL)-1β has
been widely investigated for cancer risk. In this study, we focused on the role of IL-1β …

Analysis of core genes for colorectal cancer prognosis based on immune and stromal scores

Y Zhu, Y Zhou, HG Jiang, ZH Chen, BH Lu - PeerJ, 2021 - peerj.com
Background Colorectal cancer (CRC) is one of the most common malignancies. An early
diagnosis and an accurate prognosis are major focuses of CRC research. Tumor …

IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients

M Spagnardi, J Paredes, J Zabaleta, J Garai… - Frontiers in …, 2022 - frontiersin.org
Background In the US, African Americans (AAs) present with the highest incidence and
mortality rates for Colorectal Cancer (CRC). When compared to Caucasian American (CA) …

The association between IL-1 family gene polymorphisms and colorectal cancer: A meta-analysis

L Liu, Z Zhai, D Wang, Y Ding, X Chen, Q Wang, Z Shu… - Gene, 2021 - Elsevier
Background Colorectal cancer (CRC) is a major public health problem given its high
incidence and mortality. This study focuses on examining the associations between IL-1α, IL …

Genetic ancestry and radical prostatectomy findings in Hispanic/Latino patients

NL Acosta-Vega, R Varela, JA Mesa, J Garai… - Frontiers in …, 2024 - frontiersin.org
Background African ancestry is a known factor associated with the presentation and
aggressiveness of prostate cancer (PC). Hispanic/Latino populations exhibit varying …

[HTML][HTML] Candidate SNP Markers Significantly Altering the Affinity of the TATA-Binding Protein for the Promoters of Human Genes Associated with Primary Open-Angle …

K Zolotareva, PA Dotsenko, N Podkolodnyy… - International Journal of …, 2024 - mdpi.com
Primary open-angle glaucoma (POAG) is the most common form of glaucoma. This condition
leads to optic nerve degeneration and eventually to blindness. Tobacco smoking, alcohol …