[HTML][HTML] The role of Nucleic Acid Mimics (NAMs) on FISH-based techniques and applications for microbial detection

M Nácher-Vázquez, B Santos, NF Azevedo… - Microbiological …, 2022 - Elsevier
Fluorescent in situ hybridization (FISH) is a powerful tool that for more than 30 years has
allowed to detect and quantify microorganisms as well as to study their spatial distribution in …

Recent advances in nucleic acid targeting probes and supramolecular constructs based on pyrene-modified oligonucleotides

OA Krasheninina, DS Novopashina, EK Apartsin… - Molecules, 2017 - mdpi.com
In this review, we summarize the recent advances in the use of pyrene-modified
oligonucleotides as a platform for functional nucleic acid-based constructs. Pyrene is of …

Conjugation of chemical handles and functional moieties to DNA during solid phase synthesis with sulfonyl azides

A Santorelli, KV Gothelf - Nucleic Acids Research, 2022 - academic.oup.com
Labelling of oligonucleotides with dyes, targeting ligands, and other moieties has become
ever more essential in life-sciences. Conventionally, modifications are introduced to …

Fluorophore tagged bio-molecules and their applications: A brief review

I Sarkar, AK Mishra - Applied Spectroscopy Reviews, 2018 - Taylor & Francis
Bio-molecules are principal building blocks of living species and their inter-play is the cause
of bio-activities. Various sophisticated experimental techniques as well as theoretical studies …

Acyclic Nucleic Acids with Phosphodiester Linkages—Synthesis, Properties and Potential Applications

A Tomaszewska-Antczak, P Guga - Applied Sciences, 2021 - mdpi.com
This review summarizes the synthetic efforts on acyclic analogs of nucleic acids and
provides information on the most interesting features of selected classes of such …

[HTML][HTML] Synthesis and antimicrobial activities of N6-hydroxyagelasine analogs and revision of the structure of ageloximes

B Paulsen, KA Fredriksen, D Petersen, L Maes… - Bioorganic & Medicinal …, 2019 - Elsevier
N 6-Hydroxyagelasine D, the enantiomer of the proposed structure of (−)-ageloxime D, as
well as N 6-hydroxyagelasine analogs were synthesized by selective N-7 alkylation of N 6 …

[HTML][HTML] An efficient green synthesis of UNA-nucleoside-5′-triphosphates: A versatile synthon for RNA modification with broad therapeutic potential

M Shanmugasundaram, A Senthilvelan, AR Kore - Results in Chemistry, 2023 - Elsevier
A facile, reliable, and an efficient “one-pot, two-step” method for the gram-scale chemical
synthesis of UNA-nucleoside-5′-triphosphate, starting from the commercially available …

Conformational Switching of Pyrenes Associated on Hairpin Loop Region by DNA B‐Z Transition

M Nakamura, H Yoshioka, T Takada - ChemistrySelect, 2022 - Wiley Online Library
Abstract DNA B− Z transitions play an important role in biological systems and have
attracted much attention in DNA nanotechnology. DNA and its analogues have also been …

An Efficient Gram‐Scale Chemical Synthesis of UNA‐Nucleoside‐5′‐O‐Triphosphates

A Senthilvelan, M Shanmugasundaram… - Current …, 2023 - Wiley Online Library
This unit describes a facile, reliable, and efficient method for the gram‐scale chemical
synthesis of unlocked nucleic acid‐(UNA) nucleoside‐5′‐O‐triphosphates such as UNA …

Controlling Pyrene Association in DNA Duplexes by B‐to Z‐DNA Transitions

M Nakamura, T Takada, K Yamana - ChemBioChem, 2019 - Wiley Online Library
Abstract B‐to Z‐DNA transitions play a crucial role in biological systems and have attracted
the interest of researchers for their applications in DNA nanotechnology. DNA and DNA …