In this study, we designed, synthesized, and evaluated a series of carbamate derivatives of
N-salicyloyl tryptamine as multifunctional therapeutic agents for the treatment of Alzheimer's …

In this study, a series of nitrogen‐based novel heterocyclic compounds were synthesized
and characterized by elemental analysis, IR and NMR spectra. The novel synthesized …

Flavonoids are naturally occurring polyphenolic compounds known for their extensive range
of biological activities. This review focuses on the inhibitory effects of flavonoids on …

Alzheimer's disease (AD) is one of the most common forms of dementia and is associated
with a decline in cognitive function and language ability. The deficiency of the cholinergic …

Acetylcholinesterase (AChE) is a key target for the current symptomatic treatment of
Alzheimer's disease, and galantamine is a clinical anticholinesterase drug with transiently …

The dried root of Ampelopsis japonica (Thunb.) Makino (A. japonica.) is a traditional
medicine used to treat fever, pain, and wound healing. It exhibits anti-inflammatory …

Abstract Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are enzymes that
belong to the neuromuscular cholinergic system, their main function is to hydrolyze the …

In addition to the first synthesis of the natural bromophenol butyl 2‐(3, 5‐dibromo‐4‐
hydroxyphenyl) acetate (1), indene derivatives 34 and 35 were synthesized from 3 …

Currently, of the few accessible symptomatic therapies for Alzheimer's disease (AD),
memantine is the only N-methyl-d-aspartate receptor (NMDAR) blocker approved by the …

Acetylcholinesterase (AChE) and beta-secretase (BACE-1) are the two crucial enzymes
involved in the pathology of Alzheimer's disease. The former is responsible for many defects …