Therapeutic potential of natural products in treating neurodegenerative disorders and their future prospects and challenges

MH Rahman, J Bajgai, A Fadriquela, S Sharma… - Molecules, 2021 - mdpi.com
Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …

[HTML][HTML] Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence

SF Omidkhoda, H Hosseinzadeh - Iranian Journal of Basic Medical …, 2022 - ncbi.nlm.nih.gov
Saffron, the stigmas of Crocus sativus L., has been mentioned extensively in the traditional
reference texts as a herbal medicine. Many clinical trials have been conducted on this …

Beneficial effects of saffron (Crocus sativus L.) in ocular pathologies, particularly neurodegenerative retinal diseases

JA Fernández-Albarral, R De Hoz… - Neural regeneration …, 2020 - journals.lww.com
Saffron (Crocus sativus L.) has been traditionally used in food preparation and as a
medicinal plant. It currently has numerous therapeutic properties attributed to it, such as …

Effects of crocin on diabetic maculopathy: a placebo-controlled randomized clinical trial

S Sepahi, SA Mohajeri, SM Hosseini… - American journal of …, 2018 - Elsevier
Objective Diabetic macular edema (DME) is one of the most important sight-threatening
complications in patients with diabetes. Owing to neuroprotective properties, crocin, as the …

Saffron (Crocus sativus L.) in Ocular Diseases: A Narrative Review of the Existing Evidence from Clinical Studies

R Heitmar, J Brown, I Kyrou - Nutrients, 2019 - mdpi.com
Saffron (Crocus sativus L.) and its main constituents, ie, crocin and crocetin, are natural
carotenoid compounds, which have been reported to possess a wide spectrum of properties …

The mechanical cause of age-related dementia (Alzheimer's disease): the brain is destroyed by the pulse

J Stone, DM Johnstone, J Mitrofanis… - Journal of Alzheimer's …, 2015 - content.iospress.com
This review traces evidence that age-related dementia (Alzheimer's disease) results from the
destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the …

Review of evidence for the usage of antioxidants for eye aging

PP Choo, PJ Woi, MLC Bastion, R Omar… - BioMed Research …, 2022 - Wiley Online Library
Oxidative stress is one of the common factors leading to age‐related eye diseases in older
adults. Factors such as high oxygen consumption, high concentration of polyunsaturated …

[HTML][HTML] Dietary supplements in retinal diseases, glaucoma, and other ocular conditions

MC Medori, Z Naureen, K Dhuli, G Placidi… - Journal of Preventive …, 2022 - ncbi.nlm.nih.gov
Environmental pollution, inadequate eating habits and unhealthy lifestyles have led to a
tremendous increase in ocular diseases worldwide. Given the costly treatments that are …

Neuroprotection by (endo) cannabinoids in glaucoma and retinal neurodegenerative diseases

C Rapino, D Tortolani, L Scipioni… - Current …, 2018 - ingentaconnect.com
Background: Emerging neuroprotective strategies are being explored to preserve the retina
from degeneration, that occurs in eye pathologies like glaucoma, diabetic retinopathy, age …

Saffron (Crocus sativus L.): Phytochemistry, therapeutic significance and omics-based biology

D Pandita - Medicinal and aromatic plants, 2021 - Elsevier
Crocus sativus L.(Saffron) is an economically vital medicinal and aromatic plant. Saffron is
known as the “Golden Condiment” being the world's highest priced spice (€ 30,000/kg) …