Injectable microfluidic hydrogel microspheres for cell and drug delivery
Z Zhao, Z Wang, G Li, Z Cai, J Wu… - Advanced Functional …, 2021 - Wiley Online Library
Microfluidic hydrogel microspheres have been broadly studied across a wide range of
industries and applications, and their use in the medical field, including control cells and …
industries and applications, and their use in the medical field, including control cells and …
Droplet-based microfluidics in biomedical applications
Droplet-based microfluidic systems have been employed to manipulate discrete fluid
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …
Hydrogels in emerging technologies for type 1 diabetes
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …
painless manner for patients has remained a central focus of next-generation diabetes …
[HTML][HTML] Enhancing longevity of immunoisolated pancreatic islet grafts by modifying both the intracapsular and extracapsular environment
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease characterized by
autoimmune destruction of pancreatic β cells. Transplantation of immunoisolated pancreatic …
autoimmune destruction of pancreatic β cells. Transplantation of immunoisolated pancreatic …
Advances in encapsulation and delivery strategies for islet transplantation
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease caused by the destruction of
pancreatic β‐cells in response to autoimmune reactions. Shapiro et al. conducted novel islet …
pancreatic β‐cells in response to autoimmune reactions. Shapiro et al. conducted novel islet …
Islet encapsulation: new developments for the treatment of type 1 diabetes
Q Zhang, C Gonelle-Gispert, Y Li, Z Geng… - Frontiers in …, 2022 - frontiersin.org
Islet transplantation is a promising approach for the treatment of type 1 diabetes (T1D).
Currently, clinical islet transplantation is limited by allo-and autoimmunity that may cause …
Currently, clinical islet transplantation is limited by allo-and autoimmunity that may cause …
[HTML][HTML] A novel bioartificial pancreas fabricated via islets microencapsulation in anti-adhesive core-shell microgels and macroencapsulation in a hydrogel scaffold …
H Li, Y Shang, Q Feng, Y Liu, J Chen, H Dong - Bioactive Materials, 2023 - Elsevier
Islets transplantation is a promising treatment for type 1 diabetes mellitus. However, severe
host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding …
host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding …
Synthetic scaffolds for 3D cell cultures and organoids: applications in regenerative medicine
A Marchini, F Gelain - Critical reviews in biotechnology, 2022 - Taylor & Francis
Abstract Three-dimensional (3D) cell cultures offer an unparalleled platform to recreate
spatial arrangements of cells in vitro. 3D cell culture systems have gained increasing interest …
spatial arrangements of cells in vitro. 3D cell culture systems have gained increasing interest …
Cell encapsulation and 3D bioprinting for therapeutic cell transplantation
The promise of cell therapy has been augmented by introducing biomaterials, where
intricate scaffold shapes are fabricated to accommodate the cells within. In this review, we …
intricate scaffold shapes are fabricated to accommodate the cells within. In this review, we …
Translation of cell therapies to treat autoimmune disorders
Autoimmune diseases are a diverse and complex set of chronic disorders with a substantial
impact on patient quality of life and a significant global healthcare burden. Current …
impact on patient quality of life and a significant global healthcare burden. Current …