Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Objective To identify the prevalence of people with leg ulcers resulting from sickle cell
disease, as well as to describe the clinical, social, economic, and demographic conditions of …

Vasculopathy is a hallmark of sickle cell disease ultimately resulting in chronic end organ
damage. Leg ulcer is one of its sequelae, occurring in~ 5–10% of adult sickle cell patients …

Background/objective Sickle cell disease (SCD) is a monogenic disease with multiple
phenotypic expressions. Previous studies describing SCD clinical phenotypes in Nigeria …

OBJECTIVE To define the prevalence of leg ulcers and identify the clinical and laboratory
factors associated with leg ulcers in adult participants. METHODS The authors conducted a …

Leg ulceration is a debilitating chronic complication of sickle cell disease (SCD) the
pathogenesis of which is yet to be fully elucidated. We hypothesized that SCD patients with …

Patients with sickle cell disease (SCD) often experience painful vaso‐occlusive crises and
chronic haemolytic anaemia, as well as various acute and chronic complications, such as …

BABALOLA, Oluwatoyin A. et al. Haematological indices of sickle cell patients with chronic
leg ulcers on compression therapy. Afr. J. Lab. Med.[online]. 2020, vol. 9, n. 1, pp. 1-8. ISSN …

Common, But Neglected: A Comprehensive Review of Leg Ulcers... : Advances in Skin &
Wound Care Common, But Neglected: A Comprehensive Review of Leg Ulcers in Sickle Cell …

Background Sickle cell anaemia affects about 4 million people across the globe, making it
an inherited disorder of public health importance. Red cell lysis consequent upon …