Erythropoiesis is a multi‐step process that involves the differentiation of hematopoietic stem
cells into mature red blood cells (RBCs). This process is regulated by several signaling …

Improved knowledge of all aspects of adipose biology will be required to counter the
burgeoning epidemic of obesity. Interest in adipogenesis has increased markedly over the …

Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body
insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue …

The synthesis of lipids in response to food intake represents a key advantage that allows
organisms to survive when energy availability is limited. In mammals, circulating levels of …

Background—Aging is a major risk factor for the development of atherosclerosis and
coronary artery disease. Through a microarray approach, we have identified a microRNA …

The metabolic syndrome is associated with a dysregulated adipose tissue; in part a
consequence of adipose cell enlargement and the associated infiltration of macrophages …

Breast cancer progression is highly dependent on the heterotypic interaction between tumor
cells and stromal cells of the tumor microenvironment. Cancer-associated adipocytes …

Objective 1) To evaluate whether peripheral blood mononuclear cells (PBMCs) from type 2
diabetic patients present an impairment of phagocytic activity; 2) To determine whether the …

The discovery of the GATA binding protein (GATA factor) transcription factor family
revolutionized hematology. Studies of GATA proteins have yielded vital contributions to our …

Numerous examples exist of how disrupting the actions of physiological regulators of blood
cell development yields hematologic malignancies. The master regulator of hematopoietic …