Adenine-induced animal model of chronic kidney disease: current applications and future perspectives

Q Yang, S Su, N Luo, G Cao - Renal Failure, 2024 - Taylor & Francis
Chronic kidney disease (CKD) with high morbidity and mortality all over the world is
characterized by decreased kidney function, a condition which can result from numerous risk …

The kisspeptin-1 receptor antagonist peptide-234 aggravates uremic cardiomyopathy in a rat model

H Dinh, ZZA Kovács, F Márványkövi, M Kis… - Scientific Reports, 2023 - nature.com
Uremic cardiomyopathy is characterized by diastolic dysfunction, left ventricular hypertrophy
(LVH), and fibrosis. Dysregulation of the kisspeptin receptor (KISS1R)-mediated pathways …

Thrombospondin-1 drives cardiac remodeling in chronic kidney disease

SM Julovi, K Trinh, H Robertson, C Xu, N Minhas… - Basic to Translational …, 2024 - jacc.org
Patients with chronic kidney disease (CKD) face a high risk of cardiovascular disease.
Previous studies reported that endogenous thrombospondin 1 (TSP1) involves right …

Chronic kidney disease may evoke anxiety by altering CRH expression in the amygdala and tryptophan metabolism in rats

KE Ibos, É Bodnár, H Dinh, M Kis… - … -European Journal of …, 2024 - Springer
Chronic kidney disease (CKD) is associated with anxiety; however, its exact mechanism is
not well understood. Therefore, the aim of the present study was to assess the effect of …

Role of the kisspeptin-KISS1R axis in the pathogenesis of chronic kidney disease and uremic cardiomyopathy

H Dinh, ZZA Kovács, M Kis, K Kupecz, A Sejben… - GeroScience, 2024 - Springer
The prevalence of chronic kidney disease (CKD) is increasing globally, especially in elderly
patients. Uremic cardiomyopathy is a common cardiovascular complication of CKD …

[HTML][HTML] Thrombospondin-1 in Chronic Kidney Disease Driven Cardiac Dysfunction: More Than Just a Biomarker?

A Kiss - Basic to Translational Science, 2024 - jacc.org
Chronic kidney disease (CKD) affects 15% to 20% of adults globally and increases the risk
of various cardiovascular diseases (CVDs); consequently, cardiorenal syndromes …

[HTML][HTML] Neuregulin-1: A Tonic for Cardiorenal Syndrome? And All Else That Ails Us?

AK Geissler, DB Sawyer - Basic to Translational Science, 2023 - jacc.org
The heart and kidneys are interlinked in their responsibility to maintain homeostasis. In a
state of health, the 2 organs work in a partnership to maintain—to tone—proper blood …

Effect of High-Intensity Interval Training and High-Fat Diet on Nrg-1 and Pgc-1α in Aging Rats' Heart Tissue

M Mobaseri, P Nazarali… - International Journal of …, 2024 - journals.kmanpub.com
Objective: Neuregulin is activated by exercise and has been implicated as a mediator of the
beneficial effects of exercise training on metabolism. The aim of this study was to effect of …