Metformin during pregnancy: effects on offspring development and metabolic function

G Jorquera, B Echiburú, N Crisosto… - Frontiers in …, 2020 - frontiersin.org
Maternal obesity during pregnancy and gestational diabetes mellitus (GDM) are both
associated with of several postnatal diseases in the offspring, including obesity, early onset …

Interventions in preconception and pregnant women at risk of gestational diabetes; a systematic review and meta-analysis of randomised controlled trials

OF Quotah, D Andreeva, KG Nowak… - Diabetology & Metabolic …, 2024 - Springer
Background Women at risk of gestational diabetes mellitus (GDM) need preventative
interventions. Objective To evaluate targeted interventions before and during pregnancy for …

Pregnancy, perinatal and childhood outcomes in women with and without polycystic ovary syndrome and metformin during pregnancy: a nationwide population-based …

R Fornes, J Simin, MH Nguyen, G Cruz… - Reproductive Biology …, 2022 - Springer
Abstract Background Polycystic Ovary Syndrome (PCOS) is an endocrine disorder that
affects women in reproductive age and represents an unfavourable risk factor for several …

Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis

WW Takele, KK Vesco, J Josefson… - Communications …, 2024 - nature.com
Background Lifestyle choices, metformin, and dietary supplements may prevent GDM, but
the effect of intervention characteristics has not been identified. This review evaluated …

Metformin in pregnancy to avert gestational diabetes in women at high risk: meta‐analysis of randomized controlled trials

SAR Doi, L Furuya‐Kanamori, E Toft… - Obesity …, 2020 - Wiley Online Library
Previous randomized and observational studies on the efficacy of metformin in pregnancy to
reduce incident gestational diabetes mellitus (GDM) in women at high risk (obesity …

Effects of maternal obesity on placental phenotype

AL Fowden, EJ Camm… - Current Vascular …, 2021 - ingentaconnect.com
The incidence of obesity is rising rapidly worldwide with the consequence that more women
are entering pregnancy overweight or obese. This leads to an increased incidence of clinical …

Metformin use in obese mothers is associated with improved cardiovascular profile in the offspring

O Panagiotopoulou, A Syngelaki… - American journal of …, 2020 - Elsevier
Background Maternal obesity increases the risk for pregnancy complications and adverse
neonatal outcome and has been associated with long-lasting adverse effects in the …

Childhood follow‐up of the GRoW randomized trial: Metformin in addition to dietary and lifestyle advice for pregnant women with overweight or obesity

AR Deussen, J Louise, JM Dodd - Pediatric Obesity, 2023 - Wiley Online Library
Background Metformin for women with overweight or obesity during pregnancy has been
evaluated in randomized trials to reduce adverse pregnancy and birth outcomes. The effect …

No impact of gestational diabetes mellitus on pregnancy complications in women with PCOS, regardless of GDM criteria used

SL Fougner, E Vanky, TS Løvvik, SM Carlsen - PLoS One, 2021 - journals.plos.org
Polycystic ovary syndrome (PCOS) is characterized by the presence of insulin resistance,
and women with PCOS have high prevalence of gestational diabetes (GDM). Both …

[HTML][HTML] Myoinositol and Metformin in the Prevention of Gestational Diabetes in High-Risk Patients: A Narrative Review

P Romeo, R D'Anna, F Corrado - Journal of Clinical Medicine, 2024 - mdpi.com
Our hypothesis is that myoinositol and metformin in pregnant women with high-risk factors
for glucose intolerance would reduce insulin resistance and consequently lower the …