Vestibular disorders and hormonal dysregulations: state of the art and clinical perspectives

R El Khiati, B Tighilet, S Besnard, C Chabbert - Cells, 2023 - mdpi.com
The interaction between endocrine and vestibular systems remains poorly documented so
far, despite numerous observations in humans and animals revealing direct links between …

Thyroid Axis and Vestibular Physiopathology: From Animal Model to Pathology

G Rastoldo, B Tighilet - International Journal of Molecular Sciences, 2023 - mdpi.com
A recent work of our group has shown the significant effects of thyroxine treatment on the
restoration of postural balance function in a rodent model of acute peripheral vestibulopathy …

Frontiers in neurogenesis

A Vaz, I Ribeiro, L Pinto - Cells, 2022 - mdpi.com
One of the most intriguing dogmas in neurosciences—the empirical lack of brain neuronal
regeneration in adulthood onwards to late life—began to be debunked initially by research …

mGluR1/IP3/ERK signaling pathway regulates vestibular compensation in ON UBCs of the cerebellar flocculus

D Liu, J Wang, E Tian, J Chen, W Kong… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims To investigate the role of mGluR1α in cerebellar unipolar brush cells (UBC) in
mediating vestibular compensation (VC), using mGluR1α agonist and antagonist to …

Microglial dynamics modulate vestibular compensation in a rodent model of vestibulopathy and condition the expression of plasticity mechanisms in the deafferented …

N El Mahmoudi, E Marouane, G Rastoldo, D Pericat… - Cells, 2022 - mdpi.com
Unilateral vestibular loss (UVL) induces a vestibular syndrome composed of posturo-
locomotor, oculomotor, vegetative, and perceptivo-cognitive symptoms. With time, these …

Chronic vestibular hypofunction is associated with impaired sleep: results from the DizzyReg patient registry

B Katzenberger, F Brosch, S Besnard… - Journal of Clinical …, 2023 - mdpi.com
Temporary or permanent vestibular hypofunction has been hypothesized to affect circadian
rhythm, sleep, and thermoregulation. Chronic or long-term vestibular disorders such as …

Differential modulation of cerebellar flocculus unipolar brush cells during vestibular compensation

D Liu, J Wang, L Zhou, E Tian, J Chen, W Kong, Y Lu… - Biomedicines, 2023 - mdpi.com
Vestibular compensation is a natural behavioral recovery process following unilateral
vestibular injury. Understanding the mechanism can considerably enhance vestibular …

Characterization of thyroid hormones antivertigo effects in a rat model of excitotoxically-induced vestibulopathy

CM Bringuier, B Hatat, R Boularand… - Frontiers in …, 2022 - frontiersin.org
Impaired vestibular function induces disabling symptoms such as postural imbalance,
impaired locomotion, vestibulo-ocular reflex alteration, impaired cognitive functions such as …

[HTML][HTML] 前庭代偿与治疗机制研究进展

李洁, 时海波 - Journal of Clinical Otorhinolaryngology Head and …, 2024 - ncbi.nlm.nih.gov
与其他感觉系统不同, 前庭系统通过“推-拉” 的模式维持整个系统的张力平衡,
局部功能异常增强或减弱都将导致整个系统的功能障碍。 单侧外周前庭受损将引起显著的前庭 …

[HTML][HTML] The physiological functions and polymorphisms of Type II deiodinase

Y Deng, Y Han, S Gao, W Dong… - Endocrinology and …, 2023 - synapse.koreamed.org
Type II deiodinase (DIO2) is thought to provide triiodothyronine (T3) to the nucleus to meet
intracellular needs by deiodinating the prohormone thyroxine. DIO2 is expressed widely in …