Mechanosensitive ion channels comprise a broad group of proteins that sense mechanical
extracellular and intracellular changes, translating them into cation influx to adapt and …

Genes restricted to humans may contribute to human-specific traits and provide a different
context for diseases. CHRFAM7A is a uniquely human fusion gene and a negative regulator …

Background While advancements in imaging techniques have led to major strides in
deciphering the human brain, successful interventions are elusive and represent some of …

Tumor cells metastasize from a primary lesion to distant organs mainly through
hematogenous dissemination, in which tumor cell re-adhesion to the endothelium is …

Cancer stem cells (CSCs) have been believed to be one driving force for tumor progression
and drug resistance. Despite the significance of biochemical signaling in malignancy, highly …

Background Bone marrow metastasis (BMM) is underestimated in gastric cancer (GC). GC
with BMM frequently complicate critical hematological abnormalities like diffused …

A cell's mechanical properties have been linked to cancer development, motility and
metastasis and are therefore an attractive target as a universal, reliable cancer marker. For …

The onset, development, diagnosis, and treatment of cancer involve intricate interactions
among various factors, spanning the realms of mechanics, physics, chemistry, and biology …

细胞膜是细胞与外部环境进行物质与能量交换的界面, 是调节细胞正常生命活动的重要结构基础
. 细胞膜上力敏感受体可通过力学作用方式参与并影响细胞的力信号转导等功能 …

Uncontrolled growth of tumor cells in confined spaces leads to the accumulation of
compressive stress within the tumor. Although the effects of tension within 3D extracellular …