Distinct regions harboring cancer stem cells (CSCs) have been identified within the
microenvironment of various tumors, and as in the case of their healthy counterparts, these …

Craniopharyngiomas are rare, partly cystic and calcified embryonic malformations of the
sellar/parasellar region with low histological grade (WHO Io). A bimodal age distribution has …

Senescence is a cellular stress response that results in the stable arrest of old, damaged or
pre-neoplastic cells. Oncogene-induced senescence is tumour suppressive but can also …

Hypothalamic syndrome (HS) is a rare disorder caused by disease-related and/or treatment-
related injury to the hypothalamus, most commonly associated with rare, non-cancerous …

Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with capabilities
of self-renewal, differentiation, and tumorigenicity when transplanted into an animal host. A …

This report is a review of findings on the diagnosis, treatment, clinical course, and prognosis
of craniopharyngioma patients. Craniopharyngiomas are rare, partly cystic and calcified …

Craniopharyngiomas (CPs) are clinically aggressive tumors because of their invasive
behavior and recalcitrant tendency to recur after therapy. There are 2 types based on their …

Cellular senescence is a process that results in irreversible cell-cycle arrest, and is thought
to be an autonomous tumor-suppressor mechanism. During senescence, cells develop …

Drugs that selectively kill senescent cells (senolytics) improve the outcomes of cancer,
fibrosis and age-related diseases. Despite their potential, our knowledge of the molecular …

Sox2+ adult mouse pituitary cells can self-renew and terminally differentiate in vitro, but their
physiological role in vivo and possible contribution to oncogenesis remain largely unknown …