Role of inflammatory processes in hemorrhagic stroke

SN Ohashi, JH DeLong, MG Kozberg, DJ Mazur-Hart… - Stroke, 2023 - Am Heart Assoc
Hemorrhagic stroke is the deadliest form of stroke and includes the subtypes of intracerebral
hemorrhage and subarachnoid hemorrhage. A common cause of hemorrhagic stroke in …

A practical approach to the management of cerebral amyloid angiopathy

MG Kozberg, V Perosa, ME Gurol… - … Journal of Stroke, 2021 - journals.sagepub.com
Cerebral amyloid angiopathy is a common small vessel disease in the elderly involving
vascular amyloid-β deposition. Cerebral amyloid angiopathy is one of the leading causes of …

Spontaneous ARIA-like events in cerebral amyloid angiopathy–related inflammation: a multicenter prospective longitudinal cohort study

L Antolini, JC DiFrancesco, M Zedde, G Basso… - Neurology, 2021 - AAN Enterprises
Background and Objectives The goal of this work was to investigate the natural history and
outcomes after treatment for spontaneous amyloid-related imaging abnormalities (ARIA)-like …

Validation of clinicoradiological criteria for the diagnosis of cerebral amyloid angiopathy–related inflammation

E Auriel, A Charidimou, ME Gurol, J Ni… - JAMA …, 2016 - jamanetwork.com
Importance Cerebral amyloid angiopathy–related inflammation (CAA-ri) is an important
diagnosis to reach in clinical practice because many patients with the disease respond to …

Cerebral amyloid angiopathy-related inflammation: current status and future implications

JJ Wu, M Yao, J Ni - Chinese medical journal, 2021 - mednexus.org
Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare but increasingly
recognized subtype of CAA. CAA-RI consists of two subtypes: inflammatory cerebral amyloid …

Association of microglial activation with spontaneous ARIA-E and CSF levels of anti-Aβ autoantibodies

F Piazza, SP Caminiti, M Zedde, L Presotto… - Neurology, 2022 - AAN Enterprises
Background and Objectives Amyloid-related imaging abnormalities suggestive of vasogenic
edema or sulcal effusion (ARIA-E) are the most common adverse events complicating …

Blood–brain barrier leakage and perivascular inflammation in cerebral amyloid angiopathy

MG Kozberg, I Yi, WM Freeze, CA Auger… - Brain …, 2022 - academic.oup.com
Cerebral amyloid angiopathy is a small vessel disease associated with cortical microbleeds
and lobar intracerebral haemorrhage due to amyloid-β deposition in the walls of …

Anti-Aβ autoantibodies in amyloid related imaging abnormalities (ARIA): candidate biomarker for immunotherapy in Alzheimer's disease and cerebral amyloid …

JC DiFrancesco, M Longoni, F Piazza - Frontiers in neurology, 2015 - frontiersin.org
Amyloid-related imaging abnormalities (ARIA) represent the major severe side effect of
amyloid-beta (Aβ) immunotherapy for Alzheimer's disease (AD). Early biomarkers of ARIA …

The Impact of Anti-Amyloid Immunotherapies on Stroke Care

PA Bilodeau, JR Dickson, MG Kozberg - Journal of Clinical Medicine, 2024 - mdpi.com
Anti-amyloid immunotherapies have recently emerged as treatments for Alzheimer's
disease. While these therapies have demonstrated efficacy in clearing amyloid-β and …

Amyloid-Related Imaging Abnormalities (ARIA) in immunotherapy trials for alzheimer's disease: need for prognostic biomarkers?

F Piazza, B Winblad - Journal of Alzheimer's Disease, 2016 - content.iospress.com
At the 8th International Conference on Clinical Trials in Alzheimer's Disease held November
5–7, 2015 in Barcelona, Spain, promising data were presented on two candidate …