Novel systemic treatment modalities including immunotherapy and molecular targeted therapy for recurrent and metastatic head and neck squamous cell carcinoma

S Ghosh, PA Shah, FM Johnson - International journal of molecular …, 2022 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common cancers
worldwide. More than half of patients with HNSCC eventually experience disease …

Biology of human papillomavirus infections in head and neck carcinogenesis

J Rautava, S Syrjänen - Head and neck pathology, 2012 - Springer
The association between human papillomaviruses (HPV) and oral cancer was initially
suggested nearly 30 years ago by us. Today, the research interest of head and neck …

Smoking and alcohol by HPV status in head and neck cancer: a Mendelian randomization study

A Thakral, JJW Lee, T Hou, K Hueniken… - Nature …, 2024 - nature.com
HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are
recognized as distinct entities. There remains uncertainty surrounding the causal effects of …

Current insights and progress in the clinical management of head and neck cancer

MN Amaral, P Faísca, HA Ferreira, MM Gaspar… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer (HNC) incidence has been steadily increasing
since the 1990s. While the multimodal treatment approach for localized HNC is well …

[HTML][HTML] Basics of tumor development and importance of human papilloma virus (HPV) for head and neck cancer

C Wittekindt, S Wagner, CS Mayer… - GMS current topics in …, 2012 - ncbi.nlm.nih.gov
Abstract Head and Neck Squamous Cell Carcinomas (HNSCC) are the 6 th most common
cancers worldwide. While incidence rates for cancer of the hypopharynx and larynx are …

Risk of cancer among HIV-infected individuals compared to the background population: impact of smoking and HIV

M Helleberg, J Gerstoft, S Afzal, G Kronborg… - Aids, 2014 - journals.lww.com
Background: The relative impact of immune deficiency and lifestyle-related factors on risk of
cancer in the HIV-infected population is controversial. We aimed to estimate the population …

Targeted therapy in head and neck cancer

SK Kundu, M Nestor - Tumor Biology, 2012 - Springer
Head and neck squamous cell carcinoma (HNSCC) of multi-factorial etiopathogenesis is
rising worldwide. Treatment-associated toxicity problems and treatment failure in advanced …

The association of smoking and outcomes in HPV-positive oropharyngeal cancer: a systematic review

SY Chen, S Massa, AL Mazul, D Kallogjeri… - American Journal of …, 2020 - Elsevier
Purpose While smoking is linked to worse outcomes for human papillomavirus (HPV)-
related oropharyngeal squamous cell cancer (OPSCC), the magnitude of this association …

[HTML][HTML] Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review

RSR Woods, EM O'Regan, S Kennedy… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) has been implicated in the pathogenesis of a subset of
oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the …

[HTML][HTML] Impact of HPV vaccination on HPV-related oral infections

T Gheit, R Muwonge, E Lucas, L Galati… - Oral Oncology, 2023 - Elsevier
Background Human papillomavirus (HPV) is one of the most common sexually transmitted
infections worldwide. Although the efficacy of the HPV vaccine in preventing the …