Chronic pancreatitis and pancreatic cancer risk: a systematic review and meta-analysis

J Kirkegård, FV Mortensen… - Official journal of the …, 2017 - journals.lww.com
Chronic pancreatitis is a putative risk factor for pancreatic cancer. The aim of this study was
to examine the magnitude and temporality of this association. We searched MEDLINE and …

Hepatocellular carcinoma in the setting of alcohol-related liver disease

N Ganne-Carrié, P Nahon - Journal of hepatology, 2019 - Elsevier
Alcohol-related liver disease is the most prevalent type of chronic liver disease worldwide,
accounting for 30% of hepatocellular carcinoma (HCC) cases and HCC-specific deaths …

Acute pancreatitis and pancreatic cancer risk: a nationwide matched-cohort study in Denmark

J Kirkegård, D Cronin-Fenton, U Heide-Jørgensen… - Gastroenterology, 2018 - Elsevier
Background & Aims Acute pancreatitis may be a risk factor for pancreatic cancer; however,
findings from studies on this association are conflicting. We investigated the association …

Research trends in pharmacological modulation of tumor‐associated macrophages

N Wang, S Wang, X Wang, Y Zheng… - Clinical and …, 2021 - Wiley Online Library
As one of the most abundant immune cell populations in the tumor microenvironment (TME),
tumor‐associated macrophages (TAMs) play important roles in multiple solid malignancies …

Inhibition of the CCL5/CCR5 axis against the progression of gastric cancer

D Aldinucci, N Casagrande - International journal of molecular sciences, 2018 - mdpi.com
Despite the progress made in molecular and clinical research, patients with advanced-stage
gastric cancer (GC) have a bad prognosis and very low survival rates. Furthermore, it is …

Tumour necrosis factor gene polymorphism and disease prevalence

T Qidwai, F Khan - Scandinavian journal of immunology, 2011 - Wiley Online Library
Tumour necrosis factor (TNF), an important proinflammatory cytokine, plays a role in the
regulation of cell differentiation, proliferation and death, as well as in inflammation, innate …

The role of inflammatory cytokines and tumor associated macrophages (TAMs) in microenvironment of pancreatic cancer

SF Valilou, M Keshavarz-Fathi, N Silvestris… - Cytokine & growth factor …, 2018 - Elsevier
Pancreatic cancer is considered as one of the most lethal types of cancer due to its poor
prognosis and lack of effective therapeutic approaches. Although many studies have been …

Targeting tumor stroma using engineered mesenchymal stem cells reduces the growth of pancreatic carcinoma

C Zischek, H Niess, I Ischenko, C Conrad… - Annals of …, 2009 - journals.lww.com
Objective: To analyze the efficacy of engineered mesenchymal stem cell based therapy
directed towards pancreatic tumor stroma. Summary Background Data: Mesenchymal stem …

Effect of Clostridium butyricum and Butyrate on Intestinal Barrier Functions: Study of a Rat Model of Severe Acute Pancreatitis With Intra-Abdominal Hypertension

H Zhao, L Jia, Q Yan, Q Deng, B Wei - Frontiers in physiology, 2020 - frontiersin.org
Background/Aims Severe acute pancreatitis (SAP) is associated with intra-abdominal
hypertension (IAH) and abdominal compartment syndrome (ACS), but treatment of these …

CCL5 neutralization restricts cancer growth and potentiates the targeting of PDGFRβ in colorectal carcinoma

B Cambien, P Richard-Fiardo, BF Karimdjee, V Martini… - PloS one, 2011 - journals.plos.org
Increased CCL5 levels are markers of an unfavourable outcome in patients with melanoma,
breast, cervical, prostate, gastric or pancreatic cancer. Here, we have assessed the role …