Inflammatory bowel diseases are common, complex, immune-mediated conditions with a
sharply rising global prevalence. While major advances since 2000 have provided strong …

Abstract The Inflammatory Bowel Diseases (IBD), Ulcerative Colitis (UC) and Crohn's
Disease (CD) are characterised by chronic non-resolving gut mucosal inflammation …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Abstract Background and Aims In ulcerative colitis [UC], mucosal damage occurs in areas
that are infiltrated with neutrophils. The antimicrobial function of neutrophils relies in part on …

Understanding of the pathogenesis of the coronavirus disease-2019 (COVID-19) remains
incomplete, particularly in respect to the multi-organ dysfunction it may cause. We were the …

Abstract Background and Aims Despite the presence of neutrophil extracellular traps [NETs]
in inflamed colon having been confirmed, the role of NETs, especially the circulating NETs …

Excessive release of neutrophil extracellular traps (NETs) is associated with disease
severity and contributes to tissue injury, followed by severe organ damage. Pharmacological …

NETosis is a type of regulated cell death dependent on the formation of neutrophil
extracellular traps (NET), where net-like structures of decondensed chromatin and proteases …

Neutrophils form sticky web-like structures known as neutrophil extracellular traps (NETs) as
part of innate immune response. NETs are decondensed extracellular chromatin filaments …

Autophagy is an evolutionarily conserved intracellular degradation system aiming to
maintain cell homeostasis in response to cellular stress. At physiological states, basal or …