Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …

Fluoroquinolones are broad-spectrum antimicrobials highly effective for treatment of a
variety of clinical and veterinary infections. Their antibacterial activity is due to inhibition of …

Laboratory-based in vitro antimicrobial susceptibility testing is the foundation for guiding anti-
infective therapy and monitoring antimicrobial resistance trends. We used whole-genome …

Salmonella enterica is recognized as one of the most common causes of bacterial
foodborne illness worldwide. The majority of Salmonella infections are attributed to …

The fluoroquinolones are a class of compounds that comprise a large and expanding group
of synthetic antimicrobial agents. Structurally, all fluoroquinolones contain a fluorine …

Background Food-borne salmonella infections have become a major problem in
industrialized countries. The strain of Salmonella enterica serotype typhimurium known as …

Quinolone-resistant Salmonella enterica usually contain a mutation in gyrA within the region
encoding the quinolone resistance determining region of the A subunit of DNA gyrase …

The occurrence of mutations in the genes coding for gyrase (gyrA and gyrB) and
topoisomerase IV (parE and parC) of Salmonella typhimurium experimental mutants …

Resistance of Fusarium graminearum to carbendazim is caused by point mutations in the β2-
tubulin gene. The point mutation at codon 167 (TTT→ TAT, F167Y) occurs in more than 90 …

ABSTRACT A total of 88 salmonella isolates (72 clinical isolates for which the ciprofloxacin
MIC was> 0.06 μg/ml, 15 isolates for which the ciprofloxacin MIC was≤ 0.06 μg/ml, and …