High performance binding affinity prediction with a Transformer-based surrogate model
In the current paradigm of drug discovery pipelines, identi-fication of compounds that bind to
a target with high affinity constitutes the first step. This is typically performed using resource …
a target with high affinity constitutes the first step. This is typically performed using resource …
Recognition of the tRNA structure: Everything everywhere but not all at once
J Zhang - Cell Chemical Biology, 2023 - cell.com
Summary tRNAs are among the most abundant and essential biomolecules in cells. These
spontaneously folding, extensively structured yet conformationally flexible anionic polymers …
spontaneously folding, extensively structured yet conformationally flexible anionic polymers …