Brain-on-Chip (BoC) biotechnology is emerging as a promising tool for biomedical and
pharmaceutical research applied to the neurosciences. At the convergence between lab-on …

Because of the brain's complexity, developing effective treatments for neurological disorders
is a formidable challenge. Research efforts to this end are advancing as in vitro systems …

Large-scale neural recordings with high spatial and temporal accuracy are instrumental to
understand how the brain works. To this end, it is of key importance to develop probes that …

The delivery of electrical stimuli is crucial to shape the electrophysiological activity of
neuronal populations and to appreciate the response of the different brain circuits involved …

Neural responses to the same stimulus show significant variability over trials, with this
variability typically reduced (quenched) after a stimulus is presented. This trial-to-trial …

Dissociated cortical neurons in vitro display spontaneously synchronized, low-frequency
firing patterns, which can resemble the slow wave oscillations characterizing sleep in vivo …

In the name of electroceuticals, bioelectronic devices have transformed and become
essential for dealing with all physiological responses. This significant advancement is …

Cultured neuronal networks (CNNs) have recently achieved major relevance as an
alternative to in vivo models. While many works investigate the evolution of functional …

New evidence is emerging about the dynamics of interaction between circadian rhythms and
brain waves, whose coordination occurs through the entrainment process. The so-called" …

A bidirectional in vitro brain–computer interface (BCI) directly connects isolated brain cells
with the surrounding environment, reads neural signals and inputs modulatory instructions …