In the past 20 years, earlier diagnosis and more intensive management have considerably
improved the prognosis of rheumatoid arthritis (RA), with milder disease course achieved in …

Autoimmunity refers to the phenomenon that the body's immune system produces antibodies
or sensitized lymphocytes to its own tissues to cause an immune response. Immune …

In autoimmune diseases such as rheumatoid arthritis, the immune system attacks the body's
own cells. Developing a precise understanding of the cell states where noncoding …

Idiopathic inflammatory myopathies (IIM) are rare autoimmune systemic diseases
characterized by muscle weakness and the presence of muscle‐infiltrating T cells. IIM …

Summary CD69+ CD103+ tissue-resident memory T (T RM) cells are important drivers of
inflammation. To decipher their role in inflammatory arthritis, we apply single-cell, high …

There are several autoimmune and rheumatic diseases affecting different organs of the
human body. Multiple sclerosis (MS) mainly affects brain, rheumatoid arthritis (RA) mainly …

Recent technological and algorithmic advances enable single-cell transcriptomic analysis
with remarkable depth and breadth. Nonetheless, a persistent challenge is the compromise …

Uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with
elevated levels of type 2 inflammatory cytokines and raised immunoglobulin concentrations …

Since the advent of single-cell RNA sequencing (scRNA-seq) methodology, single-cell
analysis has become a powerful tool for exploration of cellular networks and dysregulated …

Rheumatoid arthritis (RA) is a highly disabling, systemic autoimmune disease. It presents a
remarkable tendency to recur, which renders it almost impossible for patients to live without …