Immune response following traumatic spinal cord injury: Pathophysiology and therapies

RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Clinical trials of stem cell therapy for cerebral ischemic stroke

M Kawabori, H Shichinohe, S Kuroda… - International Journal of …, 2020 - mdpi.com
Despite recent developments in innovative treatment strategies, stroke remains one of the
leading causes of death and disability worldwide. Stem cell therapy is currently attracting …

Clinical trials of stem cell treatment for spinal cord injury

K Yamazaki, M Kawabori, T Seki, K Houkin - International Journal of …, 2020 - mdpi.com
There are more than one million patients worldwide suffering paralysis caused by spinal
cord injury (SCI). SCI causes severe socioeconomic problems not only to the patients and …

Modeling neurodegenerative disorders in zebrafish

AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

Neurogenesis and brain aging

NK Isaev, EV Stelmashook… - Reviews in the …, 2019 - degruyter.com
Human aging affects the entire organism, but aging of the brain must undoubtedly be
different from that of all other organs, as neurons are highly differentiated postmitotic cells …

Inflammation induces zebrafish regeneration

M Iribarne - Neural regeneration research, 2021 - journals.lww.com
Tissue or organ regeneration is a complex process with successful outcomes depending on
the type of tissue and organism. Upon damage, mammals can only efficiently restore a few …

Homeostasis and evolution in relation to regeneration and repair

A Cano‐Martínez, ME Rubio‐Ruiz… - The Journal of …, 2024 - Wiley Online Library
Homeostasis constitutes a key concept in physiology and refers to self‐regulating processes
that maintain internal stability when adjusting to changing external conditions. It diminishes …

Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury

CYP Lee, WH Chooi, SY Ng… - … & Translational Medicine, 2023 - Wiley Online Library
The neuroinflammatory response that is elicited after spinal cord injury contributes to both
tissue damage and reparative processes. The complex and dynamic cellular and molecular …

HOXA11-AS aggravates microglia-induced neuroinflammation after traumatic brain injury

XL Li, B Wang, FB Yang, LG Chen… - Neural regeneration …, 2022 - journals.lww.com
Long noncoding RNAs (lncRNAs) participate in many pathophysiological processes after
traumatic brain injury by mediating neuroinflammation and apoptosis. Homeobox A11 …

Embelin prevents seizure and associated cognitive impairments in a pentylenetetrazole-induced kindling zebrafish model

UP Kundap, YN Paudel, Y Kumari, I Othman… - Frontiers in …, 2019 - frontiersin.org
Epilepsy is a neuronal disorder associated with several neurological and behavioral
alterations characterized by recurrent spontaneous epileptic seizures. Despite having more …