New glucosamine-based TLR4 agonists: design, synthesis, mechanism of action, and in vivo activity as vaccine adjuvants

A Romerio, N Gotri, AR Franco, V Artusa… - Journal of Medicinal …, 2023 - ACS Publications
We disclose here a panel of small-molecule TLR4 agonists (the FP20 series) whose
structure is derived from previously developed TLR4 ligands (FP18 series). The new …

[图书][B] Preclinical Assessment of the Immunogenicity, Durability and Efficacy Induced by Pre-erythrocytic Vaccines Against Plasmodium falciparum Malaria

H Klingenberg - 2023 - search.proquest.com
Malaria is an ongoing global health problem caused by Plasmodium parasites that results in
the death of over half a million people each year. The majority of these deaths occur in …