Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Serotonergic psychedelics possess considerable therapeutic potential. Although 5-HT2A
receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5 …

Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Psilocybin is being investigated as a treatment in adults with treatment-resistant depression
(TRD). Withdrawal from serotonergic antidepressant drugs is a common prerequisite for …

A single dose of psilocybin, a psychedelic and serotonin 2A receptor (5-HT2AR) agonist,
may be associated with antidepressant effects. The mechanism behind its antidepressive …

A bíblia azul da farmacologia–assim tem sido mundialmente chamado este clássico
acadêmico desde o lançamento de sua 1ª edição, em 1941. A nova edição de Goodman & …

Plant-based psychedelics, such as psilocybin, have an ancient history of medicinal use.
After the first English language report on LSD in 1950, psychedelics enjoyed a short-lived …

A growing body of researches support a role for dysfunction of serotoninergic,
noradrenergic, and dopaminergic systems in the neurobiological processes involved in …

A single dose of the serotonin 2A receptor (5-HT2AR) agonist psilocybin can have long-
lasting beneficial effects on mood, personality, and potentially on mindfulness, but …