Nonalcoholic liver disease: epidemiology, risk factors, natural history, and management strategies

G Agyapong, F Dashti, BA Banini - … of the New York Academy of …, 2023 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease
worldwide and a leading indication for liver transplantation in the United States. NAFLD …

[HTML][HTML] Testosterone replacement therapy: a narrative review with a focus on new oral formulations

SZ Bhat, AS Dobs - touchREVIEWS in Endocrinology, 2022 - ncbi.nlm.nih.gov
Abstract Male hypogonadism affects 10–30% of the male population and is often under-
recognized and under-treated. Different replacement formulations exist, each with specific …

[HTML][HTML] Testosterone therapy reduces hepatic steatosis in men with type 2 diabetes and low serum testosterone concentrations

R Apostolov, E Gianatti, D Wong… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in people with
diabetes with no available treatment. AIM To explore the effect of testosterone treatment on …

A new oral testosterone (TLANDO) treatment regimen without dose titration requirement for male hypogonadism

A DelConte, K Papangkorn, K Kim, BJ Bruno… - …, 2022 - Wiley Online Library
Background Male hypogonadism (testosterone level< 300 ng/dl) is a clinical syndrome that
results from failure of the testis to produce physiological levels of testosterone. Most …

Metabolic dysfunction-associated fatty liver disease is an early predictor for testosterone deficiency in aging men without metabolic syndrome

CC Liu, SP Huang, YC Lee, CH Lee… - Frontiers in …, 2023 - frontiersin.org
Background and aims Metabolic dysfunction-associated fatty liver disease (MAFLD) has
emerged as a valuable marker for identifying individuals at increased risk of metabolic …

Safety, efficacy, and pharmacokinetics of oral testosterone undecanoate in males with hypogonadism

M Miner, C Wang, J Kaminetsky, M Khera… - …, 2024 - Wiley Online Library
Background Testosterone deficiency results from insufficient testosterone production.
Testosterone therapy may require dose titration to reach eugonadal serum testosterone …

Testosterone is lower in men with non-alcoholic fatty liver disease and alcohol-related cirrhosis and is associated with adverse clinical outcomes

R Apostolov, D Wong, E Low, K Vaz… - Scandinavian Journal …, 2023 - Taylor & Francis
Background/aims Low serum testosterone is common in cirrhotic men, but the impact of
disease aetiology remains uncertain. This study compares serum total testosterone (TT) …

[PDF][PDF] Male hypogonadism in overweight and obesity

E Armeni - Metab Target Organ Damage, 2023 - f.oaes.cc
Obesity-related gonadal dysfunction in males has been defined recently as male obesity
secondary hypogonadism (MOSH). Affected individuals present with signs and symptoms …

Newer formulations of oral testosterone undecanoate: development and liver side effects

I Goldstein, N Chidambaram, A Dobs… - Sexual medicine …, 2025 - academic.oup.com
Introduction Testosterone deficiency is a clinical disorder due to either failure of the testes to
produce testosterone or failure of the hypothalamus or pituitary to produce sufficient …

Hypogonadism and nonalcoholic fatty liver disease

K Papadimitriou, AC Mousiolis, G Mintziori… - Endocrine, 2024 - Springer
Nonalcoholic fatty liver disease (NAFLD), recently proposed to be renamed to metabolic
dysfunction-associated steatotic liver disease (MASLD), is a major global public health …