Obesity is a complex condition that is characterized by excessive fat accumulation, which
can lead to the development of metabolic disorders, such as type 2 diabetes mellitus …

Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …

Obesity is a complex, heritable trait influenced by the interplay of genetics, epigenetics,
metagenomics and the environment. With the increasing access to high precision diagnostic …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …

The prevalence of overweight and obesity in developed and developing countries has
greatly increased the risk of insulin resistance and type 2 diabetes mellitus. It is evident from …

Cognitive dysfunctions such as mild cognitive impairment (MCI), Alzheimer's disease (AD),
and other forms of dementia are recognized as common comorbidities of type 2 diabetes …

Diabetes results from the inability of pancreatic islets to maintain blood glucose
concentrations within a normal physiological range. Clinical features are usually not …

In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been
the object of intensive research. miRNAs have emerged as key mediators of metabolic …

Chronic inflammation is involved in the onset and development of many diseases, including
obesity, atherosclerosis, type 2 diabetes, osteoarthritis, autoimmune and degenerative …

Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …