Genetic polymorphism varies among species and within genomes, and has important
implications for the evolution and conservation of species. The determinants of this variation …

Accumulating evidence suggests that many classes of DNA repeats exhibit attributes that
distinguish them from other genetic variants, including the fact that they are more liable to …

Short tandem repeats (STRs) are highly variable elements that play a pivotal role in multiple
genetic diseases, population genetics applications, and forensic casework. However, it has …

Microsatellites, or simple sequence repeats (SSRs), are one of the most informative and
multi-purpose genetic markers exploited in plant functional genomics. However, the …

Next generation sequencing (NGS) is challenged by structural and copy number variations
larger than the typical read length of several hundred bases. Third-generation sequencing …

Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
accurately profiling STRs from high-throughput sequencing data have enabled genome …

Approximately 13% of the human genome at certain motifs have the potential to form
noncanonical (non-B) DNA structures (eg, G-quadruplexes, cruciforms, and Z-DNA), which …

Finger millet is an important cereal crop in eastern Africa and southern India with excellent
grain storage quality and unique ability to thrive in extreme environmental conditions. Since …

Abstract Background Y-chromosome DNA (Y-DNA) has been used for tracing paternal
lineages and offers a clear path from an individual to a known, or likely, direct paternal …

Background Microsatellite repeats are ubiquitous in organism genomes and play an
important role in the chromatin organization, regulation of gene activity, recombination and …