The microbiota–gut–brain axis and neurodevelopmental disorders

Q Wang, Q Yang, X Liu - Protein & Cell, 2023 - academic.oup.com
The gut microbiota has been found to interact with the brain through the microbiota–gut–
brain axis, regulating various physiological processes. In recent years, the impacts of the gut …

Western diets and chronic diseases

TE Adolph, H Tilg - Nature Medicine, 2024 - nature.com
Abstract 'Westernization', which incorporates industrial, cultural and dietary trends, has
paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style …

[HTML][HTML] Investigating the shared genetic architecture between COVID-19 and obesity: a large-scale genome wide cross-trait analysis

Y Chen, C Fan, J Liu - Frontiers in Endocrinology, 2024 - frontiersin.org
Observational studies have reported high comorbidity between obesity and severe COVID-
19. The aim of this study is to explore whether genetic factors are involved in the co …

[HTML][HTML] Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics

A Arora, M Becker, C Marques, M Oksanen, D Li… - Scientific Reports, 2023 - nature.com
Research continues to identify genetic variation, environmental exposures, and their
mixtures underlying different diseases and conditions. There is a need for screening …

[HTML][HTML] A lipidomic based metabolic age score captures cardiometabolic risk independent of chronological age

T Wang, HB Beyene, C Yi, M Cinel, NA Mellett… - eBioMedicine, 2024 - Elsevier
Background Metabolic ageing biomarkers may capture the age-related shifts in metabolism,
offering a precise representation of an individual's overall metabolic health. Methods …

Blood Lipids, Lipoproteins, and Apolipoproteins With Risk of Coronary Heart Disease: A Prospective Study Among Racially Diverse Populations

K Deng, XF Pan, MW Voehler, Q Cai, H Cai… - Journal of the …, 2024 - Am Heart Assoc
Background Comprehensive blood lipoprotein profiles and their association with incident
coronary heart disease (CHD) among racially and geographically diverse populations …

[HTML][HTML] Additive interaction between birth asphyxia and febrile seizures on autism spectrum disorder: a population-based study

Y Mao, X Lin, Y Wu, J Lu, J Shen, S Zhong, X Jin, J Ma - Molecular Autism, 2024 - Springer
Abstract Background Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental
disorder that can significantly impact an individual's ability to socially integrate and adapt. It's …

Absence of Causal Relationship Between Levels of Unsaturated Fatty Acids and ADHD: Evidence From Mendelian Randomization Study

Z Wang, H Zhu, L Chen, C Gan, W Min… - Journal of Attention …, 2024 - journals.sagepub.com
Objective: Previous research suggests a potential link between unsaturated fatty acids
(UFAs) and ADHD, but the causal relationship remains uncertain. This study aims to …

Neuropsychiatric biomarker discovery: go big or go home

A Ljungdahl, SJ Sanders - Trends in molecular medicine, 2023 - cell.com
Technological advances have enabled high-throughput omics assays, such as parallelized
screening of lipids across plasma samples. Pioneering a new paradigm for neuropsychiatric …

[HTML][HTML] Metabolomic changes in children with autism

M Al-Beltagi, NK Saeed, AS Bediwy… - World Journal of Clinical …, 2024 - wjgnet.com
BACKGROUND Autism spectrum disorder (ASD) is a neurodevelopmental condition
characterized by deficits in social communication and repetitive behaviors. Metabolomic …