Twenty years of amino acid determination using capillary electrophoresis: A review

HY Ta, F Collin, L Perquis, V Poinsot, V Ong-Meang… - Analytica chimica …, 2021 - Elsevier
In this review, we have attempted to highlight the advancements in the the field of 17 amino
acid determination using capillary electrophoresis. The technique has been developed 18 …

A ketogenic diet modifies glutamate, gamma-aminobutyric acid and agmatine levels in the hippocampus of rats: A microdialysis study

N Calderón, L Betancourt, L Hernández, P Rada - Neuroscience letters, 2017 - Elsevier
The ketogenic diet (KD) is acknowledged as an unconventional option in the treatment of
epilepsy. Several lines of investigation point to a possible role of glutamate and gamma …

Participation of hippocampal agmatine in spatial learning: an in vivo microdialysis study

M Rushaidhi, Y Jing, H Zhang, P Liu - Neuropharmacology, 2013 - Elsevier
Agmatine, decarboxylated arginine, is widely distributed in mammalian brains and is
considered as a novel putative neurotransmitter. Recent research demonstrates spatial …

A machine learning approach to predict pancreatic islet grafts rejection versus tolerance

GA Ceballos, LF Hernandez, D Paredes… - PloS one, 2020 - journals.plos.org
The application of artificial intelligence (AI) and machine learning (ML) in biomedical
research promises to unlock new information from the vast amounts of data being generated …

Agmatine attenuates neuropathic pain in sciatic nerve ligated rats: modulation by hippocampal sigma receptors

NR Kotagale, SH Shirbhate, P Shukla… - European journal of …, 2013 - Elsevier
Present study investigated the influence of the sigma (σ 1 and σ 2) receptors within
hippocampus on the agmatine induced antinociception in neuropathic rats. Animals were …

Feasibility of localized metabolomics in the study of pancreatic islets and diabetes

O Alcazar, LF Hernandez, A Tschiggfrie… - Metabolites, 2019 - mdpi.com
(1) Background: Disruption of insulin production by native or transplanted pancreatic islets
caused by auto/allo-immunity leads to hyperglycemia, a serious health condition and …

Amino acid profile of plasma and cerebrospinal fluid in preeclampsia

Y Terán, O Ponce, L Betancourt, L Hernández… - … An International Journal …, 2012 - Elsevier
Objectives To determine patterns in amino acids (arginine, GABA, glutamate and glutamine)
and the diamine (agmatine) in plasma and cerebrospinal fluid (CSF) of mild and severe …

Putative agmatinase inhibitor for hypoxic-ischemic new born brain damage

JE Piletz, S Klenotich, KS Lee, QL Zhu, E Valente… - Neurotoxicity …, 2013 - Springer
Agmatine is an endogenous brain metabolite, decarboxylated arginine, which has
neuroprotective properties when injected intraperitoneally (ip) into rat pups following …

Microdialysis in CNS PKPD research: unraveling unbound concentrations

M Hammarlund-Udenaes - Microdialysis in drug development, 2012 - Springer
The pharmacokinetic (PK) processes of drug movements between blood and tissues and the
drug concentration profiles within a tissue over time can be described with the help of …

同位素稀释-气相色谱-质谱法检测大鼠血浆中的内源性胍丁胺

丘忠丽, 林缨, 熊志立, 谢剑炜 - 色谱, 2014 - chrom-china.com
建立了大鼠血浆中内源性胍丁胺的同位素稀释-气相色谱-负化学电离质谱定量分析方法.
大鼠血浆样品经蛋白沉淀并蒸干后, 用六氟乙酰丙酮衍生化, 采用Florisil 固相萃取柱净化 …