The ketogenic diet (KD) is acknowledged as an unconventional option in the treatment of epilepsy. Several lines of investigation point to a possible role of glutamate and gamma …
M Rushaidhi, Y Jing, H Zhang, P Liu - Neuropharmacology, 2013 - Elsevier
Agmatine, decarboxylated arginine, is widely distributed in mammalian brains and is considered as a novel putative neurotransmitter. Recent research demonstrates spatial …
The application of artificial intelligence (AI) and machine learning (ML) in biomedical research promises to unlock new information from the vast amounts of data being generated …
NR Kotagale, SH Shirbhate, P Shukla… - European journal of …, 2013 - Elsevier
Present study investigated the influence of the sigma (σ 1 and σ 2) receptors within hippocampus on the agmatine induced antinociception in neuropathic rats. Animals were …
O Alcazar, LF Hernandez, A Tschiggfrie… - Metabolites, 2019 - mdpi.com
(1) Background: Disruption of insulin production by native or transplanted pancreatic islets caused by auto/allo-immunity leads to hyperglycemia, a serious health condition and …
Y Terán, O Ponce, L Betancourt, L Hernández… - … An International Journal …, 2012 - Elsevier
Objectives To determine patterns in amino acids (arginine, GABA, glutamate and glutamine) and the diamine (agmatine) in plasma and cerebrospinal fluid (CSF) of mild and severe …
Agmatine is an endogenous brain metabolite, decarboxylated arginine, which has neuroprotective properties when injected intraperitoneally (ip) into rat pups following …
The pharmacokinetic (PK) processes of drug movements between blood and tissues and the drug concentration profiles within a tissue over time can be described with the help of …