Epithelial and endothelial cells possess the inherent plasticity to undergo morphological,
cellular, and molecular changes leading to their resemblance of mesenchymal cells. A …

The USA is currently going through an opioid crisis, associated with tremendous economic
and societal impacts. In response to this crisis, healthcare professionals are looking for …

Uncontrolled inflammation is linked to poor outcomes in sepsis and wound healing, both of
which proceed through distinct inflammatory and resolution phases. Eicosanoids are a class …

Background Impaired wound healing is a debilitating complication of diabetes that leads to
significant morbidity, particularly foot ulcers. The risk of developing diabetic foot ulcers for …

Successful treatment of skin infections requires eradication of biofilms found in up to 90% of
all chronic wounds, causing delayed healing and increased morbidity. We hypothesized that …

In the last years, extracellular vesicles (EVs) from different plant matrices have been isolated
and gained the interest of the scientific community for their intriguing biological properties. In …

The ischaemia‐reperfusion (I/R)–induced skin lesion has been identified as primary cause
of pressure ulcers. To date, attempts to prevent pressure ulcers have not produced a …

The article presents an experimental study on the possible repurposed use of valsartan
(Val), in the local treatment of uncontrolled diabetic foot ulcer. Solid lipid nanoparticles …

This study was aimed to explore the mechanism of rutaecarpine (RUT) on ethanol-induced
gastric ulcer (GU) in mice by integrated approaches. At first, the efficacy was determined …

Chronic wounds are a major healthcare challenge around the world. The presence of
bacterial biofilms, accumulation of reactive oxygen species (ROS), and persistent …